STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO1925Putative sensor protein (pseudogene); 1 probable transmembrane helix predicted. (210 aa)    
Predicted Functional Partners:
barA
Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa.
 
 0.994
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
 
 0.970
YPO3965
Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa.
 
 0.901
YPO0256
Two-component sensor/regulator; Similar to Salmonella typhimurium pathogenicity island regulator gene SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 46.5% id in 826 aa and to Vibrio cholerae sensory box sensor histidine kinase/response regulator VieS VC1653 TR:Q9KRI8 (EMBL:AE004243) (1146 aa) fasta scores: E(): 0, 30.4% id in 559 aa. This CDS carries both the sensor and response regulator domains.
 
 0.876
rcsC
Two component sensor kinase/response regulator protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
0.835
narR
Nitrate/nitrite sensor protein; Previously sequenced as Yersinia pestis probable nitrate/nitrite sensor protein TR:Q9ZC64 (EMBL:AL031866) (593 aa) fasta scores: E(): 0, 100.0% id in 593 aa. Similar to Escherichia coli nitrate/nitrite sensor protein NarX SW:NARX_ECOLI (P10956) (598 aa) fasta scores: E(): 0, 47.9% id in 595 aa.
 
 0.806
YPO0998
Putative membrane protein; Similar to Pseudomonas aeruginosa conserved hypothetical protein PA2072 TR:AAG05460 (EMBL:AE004634) (864 aa) fasta scores: E(): 0, 43.7% id in 773 aa, and to C-terminus of Pseudomonas aeruginosa conserved hypothetical protein PA4601 TR:AAG07989 (EMBL:AE004874) (1415 aa) fasta scores: E(): 0, 42.2% id in 460 aa.
 
 0.712
rstA
Similar to Escherichia coli transcriptional regulatory protein RstA SW:RSTA_ECOLI (P52108) (242 aa) fasta scores: E(): 0, 73.9% id in 245 aa, and to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP SW:PHOP_BACSU (P13792) (240 aa) fasta scores: E(): 1.3e-20, 33.5% id in 239 aa.
  
  0.688
aer
Putative methyl-accepting chemotaxis protein; Similar to Escherichia coli aerotaxis receptor Aer or Air SW:AER_ECOLI (P50466) (506 aa) fasta scores: E(): 0,47.1% id in 514 aa, and to Escherichia coli methyl-accepting chemotaxis protein II Tar or CheM SW:MCP2_ECOLI (P07017) (553 aa) fasta scores: E(): 0, 43.3% id in 360 aa.
 
 0.674
YPO3958
Similar to Escherichia coli transcriptional regulatory protein OmpR SW:OMPR_ECOLI (P03025) (239 aa) fasta scores: E(): 9.6e-27, 37.1% id in 237 aa, and to Zymomonas mobilis aerobic respiration control protein ArcA TR:Q9X3W0 (EMBL:AF088896) (241 aa) fasta scores: E(): 8.5e-30, 39.2% id in 240 aa.
  
  0.658
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.