Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
hutIImidazolonepropionase; Previously sequenced as Yersinia pestis hypothetical protein HutI SW:HUTI_YERPE (Q9ZC74) (406 aa) fasta scores: E(): 0, 100.0% id in 406 aa. Similar to Pseudomonas putida imidazolonepropionase HutI SW:HUTI_PSEPU (O31200) (400 aa) fasta scores: E(): 0, 54.2% id in 408 aa; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (406 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 
 0.999
YPO1974
Putative chlorohydrolase; Previously sequenced Yersinia pestis hypothetical protein TR:Q9ZC76 (EMBL:AL031866) (456 aa) fasta scores: E(): 0, 100.0% id in 456 aa. Similar to Myxococcus xanthus SdeB protein, which is essential for development and sporulation, TR:O68982 (EMBL:AF060075) (462 aa) fasta scores: E(): 0, 36.6% id in 421 aa.
 
 
 0.994
hutH
Similar to Pseudomonas putida histidine ammonia-lyase HutH SW:HUTH_PSEPU (P21310) (509 aa) fasta scores: E(): 0, 78.3% id in 507 aa, and to Pseudomonas aeruginosa histidine ammonia-lyase HutH TR:AAG08483 (EMBL:AE004922) (509 aa) fasta scores: E(): 0, 78.0% id in 508 aa; Belongs to the PAL/histidase family.
 
  
 0.994
hutG
Putative N-formylglutamate amidohydrolase; Previously sequenced Yersinia pestis hypothetical protein HutG TR:Q9ZC73 (EMBL:AL031866) (268 aa) fasta scores: E(): 0, 100.0% id in 268 aa. Similar to Pseudomonas putida N-formylglutamate amidohydrolase HutG TR:O31201 (EMBL:AF032970) (267 aa) fasta scores: E(): 0, 59.6% id in 260 aa.
 
  
 0.986
hutC
Putative GntR-family transcriptional regulatory protein; Previously sequenced as Yersinia pestis hypothetical protein HutC TR:Q9ZC75 (EMBL:AL031866) (255 aa) fasta scores: E(): 0, 99.6% id in 255 aa. Similar to Pseudomonas putida histidine utilization repressor HutC SW:HUTC_PSEPU (P22773) (248 aa) fasta scores: E(): 0, 63.2% id in 242 aa.
 
 
 0.926
YPO1975
Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC77 (EMBL:AL031866) (190 aa) fasta scores: E(): 0, 100.0% id in 190 aa and to Escherichia coli hypothetical protein YdjR SW:YDJR_ECOLI (P76214) (191 aa) fasta scores: E(): 2.9e-18, 39.2% id in 171 aa.
 
  
 0.673
YPO2778
Similar to Escherichia coli hypothetical protein YfcH SW:YFCH_ECOLI (P77775) (297 aa) fasta scores: E(): 0,68.8% id in 298 aa, and to Pseudomonas aeruginosa hypothetical protein PA4656 TR:AAG08043 (EMBL:AE004879) (305 aa) fasta scores: E(): 0, 49.3% id in 298 aa.
  
    0.508
proW
Similar to Escherichia coli glycine betaine/L-proline transport system permease protein ProW SW:PROW_ECOLI (P14176) (354 aa) fasta scores: E(): 0, 76.6% id in 372 aa, and to Pseudomonas putida glycine betaine/L-proline transport system permease protein ProW TR:Q9L7Y9 (EMBL:AF218267) (315 aa) fasta scores: E(): 0,62.6% id in 305 aa. CDS contain an extended N-terminus,possible alternative translational start sites.
  
    0.493
proV
Similar to Escherichia coli glycine betaine/L-proline transport ATP-binding protein ProV SW:PROV_ECOLI (P14175) (400 aa) fasta scores: E(): 0, 81.7% id in 398 aa, and to Salmonella typhimurium glycine betaine/L-proline transport ATP-binding protein ProV SW:PROV_SALTY (P17328) (400 aa) fasta scores: E(): 0, 81.2% id in 398 aa.
  
    0.487
kdgR
IclR-family transcriptional regulatory protein; Similar to Pectobacterium carotovorum subsp. cartovorum KdgR TR:Q9RB24 (EMBL:AF135396) (263 aa) fasta scores: E(): 0, 89.0% id in 263 aa, and to Escherichia coli transcriptional regulator KdgR SW:KDGR_ECOLI (P76268) (263 aa) fasta scores: E(): 0, 86.3% id in 263 aa.
    
 0.474
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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