Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hutCPutative GntR-family transcriptional regulatory protein; Previously sequenced as Yersinia pestis hypothetical protein HutC TR:Q9ZC75 (EMBL:AL031866) (255 aa) fasta scores: E(): 0, 99.6% id in 255 aa. Similar to Pseudomonas putida histidine utilization repressor HutC SW:HUTC_PSEPU (P22773) (248 aa) fasta scores: E(): 0, 63.2% id in 242 aa. (255 aa)    
Predicted Functional Partners:
YPO1975
Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC77 (EMBL:AL031866) (190 aa) fasta scores: E(): 0, 100.0% id in 190 aa and to Escherichia coli hypothetical protein YdjR SW:YDJR_ECOLI (P76214) (191 aa) fasta scores: E(): 2.9e-18, 39.2% id in 171 aa.
 
  
 0.957
hutI
Imidazolonepropionase; Previously sequenced as Yersinia pestis hypothetical protein HutI SW:HUTI_YERPE (Q9ZC74) (406 aa) fasta scores: E(): 0, 100.0% id in 406 aa. Similar to Pseudomonas putida imidazolonepropionase HutI SW:HUTI_PSEPU (O31200) (400 aa) fasta scores: E(): 0, 54.2% id in 408 aa; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.926
hutG
Putative N-formylglutamate amidohydrolase; Previously sequenced Yersinia pestis hypothetical protein HutG TR:Q9ZC73 (EMBL:AL031866) (268 aa) fasta scores: E(): 0, 100.0% id in 268 aa. Similar to Pseudomonas putida N-formylglutamate amidohydrolase HutG TR:O31201 (EMBL:AF032970) (267 aa) fasta scores: E(): 0, 59.6% id in 260 aa.
 
 
 0.881
b4390
Similar to Salmonella typhimurium transcriptional regulator NadR SW:NADR_SALTY (P24518) (409 aa) fasta scores: E(): 0, 85.0% id in 406 aa, and to Escherichia coli transcriptional regulator NadR SW:NADR_ECOLI (P27278) (410 aa) fasta scores: E(): 0, 83.7% id in 406 aa.
   
  
 0.874
YPO1974
Putative chlorohydrolase; Previously sequenced Yersinia pestis hypothetical protein TR:Q9ZC76 (EMBL:AL031866) (456 aa) fasta scores: E(): 0, 100.0% id in 456 aa. Similar to Myxococcus xanthus SdeB protein, which is essential for development and sporulation, TR:O68982 (EMBL:AF060075) (462 aa) fasta scores: E(): 0, 36.6% id in 421 aa.
 
  
 0.870
hutH
Similar to Pseudomonas putida histidine ammonia-lyase HutH SW:HUTH_PSEPU (P21310) (509 aa) fasta scores: E(): 0, 78.3% id in 507 aa, and to Pseudomonas aeruginosa histidine ammonia-lyase HutH TR:AAG08483 (EMBL:AE004922) (509 aa) fasta scores: E(): 0, 78.0% id in 508 aa; Belongs to the PAL/histidase family.
 
  
 0.840
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.827
YPO2762
Putative AraC-family regulatory protein; Similar to Vibrio cholerae putative transcriptional AraC/XylS family regulator VCA0937 TR:Q9KL12 (EMBL:AE004420) (263 aa) fasta scores: E(): 0, 45.6% id in 241 aa, and to Vibrio cholerae putative AraC type transcriptional regulator TR:Q9L4Y9 (EMBL:AF262020) (241 aa) fasta scores: E(): 0, 46.8% id in 233 aa.
  
  
 0.702
nifJ
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa.
    
  0.692
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.571
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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