Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YPO1982Putative dehydrogenase; Similar to Pseudomonas aeruginosa WbpK TR:P72144 (EMBL:U50396) (320 aa) fasta scores: E(): 2.8e-07, 29.8% id in 258 aa, and to Pseudomonas aeruginosa WbjfT TR:Q9KIC7 (EMBL:AF236052) (301 aa) fasta scores: E(): 7.7e-07, 27.0% id in 270 aa, and to Yersinia enterocolitica putative 6-deoxy-gulose synthetase-2 WbcB TR:Q56863 (EMBL:U46859) (292 aa) fasta scores: E(): 4e-06, 27.0% id in 256 aa. Proteins WbpK and WbjfT from P.aeruginosa and WbcB from Y. enterocolitica are all involved in O antigen biosynthesis. (320 aa)    
Predicted Functional Partners:
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 0.865
YPO1985
Putative glycosyl transferase; Similar to Streptomyces fradiae deoxyallosyl-transferase TylN TR:O70023 (EMBL:AJ005397) (422 aa) fasta scores: E(): 1e-08, 24.1% id in 370 aa, and to Saccharothrix aerocolonigenes Ngt protein TR:Q9S595 (EMBL:AB023953) (414 aa) fasta scores: E(): 1e-08, 24.0% id in 375 aa.
 
  
 0.850
YPO1983
Putative glycosyl transferase; Similar to Mus musculus ceramide glucosyltransferase UgcG TR:O88693 (EMBL:D89866) (394 aa) fasta scores: E(): 2.3e-10, 24.2% id in 389 aa, and to Rattus norvegicus ceramide glucosyltransferase TR:Q9R0E0 (EMBL:AF047707) (394 aa) fasta scores: E(): 5.8e-10, 23.9% id in 389 aa. These enzymes are involved in lipid glycosylation.
 
 
 0.834
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.800
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.785
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
  0.780
neaA
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.775
YPO1984
Hypothetical protein; Doubtful CDS. No significant database hits.
       0.773
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
   
  0.762
rpsl
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
  0.761
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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