STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
YPO1985Putative glycosyl transferase; Similar to Streptomyces fradiae deoxyallosyl-transferase TylN TR:O70023 (EMBL:AJ005397) (422 aa) fasta scores: E(): 1e-08, 24.1% id in 370 aa, and to Saccharothrix aerocolonigenes Ngt protein TR:Q9S595 (EMBL:AB023953) (414 aa) fasta scores: E(): 1e-08, 24.0% id in 375 aa. (395 aa)    
Predicted Functional Partners:
YPO1983
Putative glycosyl transferase; Similar to Mus musculus ceramide glucosyltransferase UgcG TR:O88693 (EMBL:D89866) (394 aa) fasta scores: E(): 2.3e-10, 24.2% id in 389 aa, and to Rattus norvegicus ceramide glucosyltransferase TR:Q9R0E0 (EMBL:AF047707) (394 aa) fasta scores: E(): 5.8e-10, 23.9% id in 389 aa. These enzymes are involved in lipid glycosylation.
 
     0.940
YPO1982
Putative dehydrogenase; Similar to Pseudomonas aeruginosa WbpK TR:P72144 (EMBL:U50396) (320 aa) fasta scores: E(): 2.8e-07, 29.8% id in 258 aa, and to Pseudomonas aeruginosa WbjfT TR:Q9KIC7 (EMBL:AF236052) (301 aa) fasta scores: E(): 7.7e-07, 27.0% id in 270 aa, and to Yersinia enterocolitica putative 6-deoxy-gulose synthetase-2 WbcB TR:Q56863 (EMBL:U46859) (292 aa) fasta scores: E(): 4e-06, 27.0% id in 256 aa. Proteins WbpK and WbjfT from P.aeruginosa and WbcB from Y. enterocolitica are all involved in O antigen biosynthesis.
 
  
 0.850
YPO1984
Hypothetical protein; Doubtful CDS. No significant database hits.
       0.801
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 
 0.766
YPO1979
Similar to Salmonella typhimurium 3-oxoacyl-[acyl-carrier-protein] synthase III SW:FABH_SALTY (O85139) (317 aa) fasta scores: E(): 2.4e-21, 29.0% id in 314 aa, and to Xanthomonas campestris GumO TR:O34266 (EMBL:U70053) (435 aa) fasta scores: E(): 0, 38.3% id in 329 aa, and identical over its N-terminal and C-terminal regions to the previously sequenced Yersinia pestis Q9ZC79 and Q9ZC80, respectively. There is a possible frameshift mutation following codon 158. The sequence has been checked and is believed to be correct.
 
  
 0.610
YPO0308
Putative oxidoreductase; Similar to the eukaryotic Chondrus crispus (red algae) hexose oxidase TR:P93762 (EMBL:U89770) (546 aa) fasta scores: E(): 0, 33.8% id in 551 aa. Note the C-terminus of this protein is similar to many chitinases e.g. Serratia marcescens ChiC TR:Q9WXD3 (EMBL:AB019238) (480 aa) fasta scores: E(): 2.1e-15, 43.1% id in 144 aa.
   
  
 0.598
YPO0776
Putative siderophore biosysnthesis protein; Similar to N-terminus of Yersinia pestis yersiniabactin biogenesis protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 31.1% id in 1659 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF TR:Q9RFM7 (EMBL:AF184622) (1809 aa) fasta scores: E(): 0, 34.1% id in 1957 aa. and to Vibrio anguillarum anguibactin biosynthesis protein AngR SW:ANGR_VIBAN (P19828) (1048 aa) fasta scores: E(): 0, 32.1% id in 844 aa. CDS contains a glutamine and threonine rich imperfect repeat region, residues 996 to 1065.
     
 0.595
YPO1980
Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC82 (EMBL:AL031866) (268 aa) fasta scores: E(): 0, 100.0% id in 268 aa. Similar to Xanthomonas campestris hypothetical protein GumP TR:O34267 (EMBL:U70053) (282 aa) fasta scores: E(): 1.4e-22, 33.7% id in 252 aa.
 
     0.584
YPO1981
Putative coenzyme synthetase; Similar to Methanobacterium thermoautotrophicum coenzyme F390 synthetase III Mth161 TR:O26263 (EMBL:AE000804) (434 aa) fasta scores: E(): 0.00035, 21.2% id in 448 aa, and to Vibrio cholerae CapK protein, putative Vc0924 TR:Q9KTH8 (EMBL:AE004175) (446 aa) fasta scores: E(): 1.9e-08, 24.4% id in 336 aa.
       0.552
irp2
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 100.0% id in 2035 aa. Similar to Yersinia enterocolitica high-molecular-weight protein 2 Irp2 SW:HMP2_YEREN (P48633) (2035 aa) fasta scores: E(): 0, 98.6% id in 2035 aa. The previously sequenced Yersinia pestis Irp2 ORF starts at a valine situated 6 aa upstream from the methionine. However,the methionine start, has a good ribosome-binding site.
  
  
 0.488
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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