STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO1990Putative membrane protein; Its internal region shows some similarity to Neisseria meningitidis hypothetical protein Nma1541 TR:Q9JU20 (EMBL:AL162756) (477 aa) fasta scores: E(): 0.21,25.7% id in 241 aa, and to Mycobacterium tuberculosis hypothetical 60.2 kDa protein Rv1135C or Mtci65.02C TR:O06535 (EMBL:Z95584) (618 aa) fasta scores: E(): 2,27.2% id in 184 aa. (703 aa)    
Predicted Functional Partners:
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.656
flgC
Similar to Escherichia coli flagellar basal-body rod protein FlgC SW:FLGC_ECOLI (P75935) (134 aa) fasta scores: E(): 5.2e-17, 46.1% id in 141 aa, and to Vibrio parahaemolyticus possible flagellar basal-body rod protein LfgC TR:Q56720 (EMBL:U51896) (144 aa) fasta scores: E(): 6.8e-28, 57.0% id in 142 aa.
   
   0.648
fla-4
Similar to Salmonella typhimurium flagellar basal-body rod protein FlgC or FlaW or Fla FIII SW:FLGC_SALTY (P16438) (134 aa) fasta scores: E(): 0, 79.9% id in 134 aa, and to Yersinia enterocolitica flagellar basal-body rod protein FlgC SW:FLGC_YEREN (Q56894) (134 aa) fasta scores: E(): 0, 96.3% id in 134 aa.
   
   0.648
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
   
 0.594
YPO3010
Hypothetical protein; Weakly similar to the N-terminal and central regions of the previously sequenced Yersinia pestis outer membrane protein YopM or Yop48 SW:YOPM_YERPE (P17778) (367 aa) fasta scores: E(): 0.00012, 29.9% id in 177 aa, and to phage Gifsy-1 leucine-rich repeat protein GogB TR:Q9MBM1 (EMBL:AF254761) (489 aa) fasta scores: E(): 1.4e-19, 36.9% id in 360 aa.
    
   0.481
poaA
Bifunctional PutA protein [includes: proline dehydrogenase and delta-1-pyrroline-5-carboxylate; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
    
  0.445
YPO1991
Putative sugar-phosphate isomerase; Similar to Escherichia coli ribose 5-phosphate isomerase B RpiB SW:RPIB_ECOLI (P37351) (149 aa) fasta scores: E(): 1.6, 28.3% id in 145 aa, and to Thermotoga maritima sugar-phosphate isomerase Tm1080 TR:Q9X0G9 (EMBL:AE001768) (143 aa) fasta scores: E(): 0.15, 32.0% id in 125 aa.
       0.423
glpF
Glycerol kinase (pseudogene); PS00933 FGGY family of carbohydrate kinases signature 1; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.410
YPO0593
Hypothetical protein; Poor database hits. Internal region of the CDS similar to internal region of Saccharomyces cerevisiae hypothetical protein YAR002w SW:YAH2_YEAST (P39705) (539 aa) fasta scores: E(): 0.21, 22.3% id in 224 aa.
   
   0.409
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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