Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YPO1995Hypothetical protein; Weakly similar to Escherichia coli O157:H7 Z0020 protein Z0020 TR:AAG54319 (EMBL:AE005178) (207 aa) fasta scores: E(): 6.6, 26.3% id in 156 aa. The similarity is limited to the central and C-terminal regions of this CDS. (310 aa)    
Predicted Functional Partners:
YPO1996
Hypothetical protein; No significant database hits.
       0.797
aspB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 87.4% id in 1497 aa, and to Vibrio cholerae glutamate synthase, large subunit Vc2376 TR:Q9KPJ1 (EMBL:AE004308) (1487 aa) fasta scores: E(): 0, 73.7% id in 1488 aa.
    
 0.774
YPO1994
Hypothetical protein; Weakly similar to the internal region of Saccharomyces cerevisiae nonsense-mediated mRNA decay protein 2 Nmd2 or Upf2 or ifs1 or Sua1 or Yhr077C SW:NMD2_YEAST (P38798) (1089 aa) fasta scores: E(): 0.15,26.0% id in 289 aa. It also shows similarity to the N-terminus of Mus musculus calreticulin precursor CalR SW:CRTC_MOUSE (P14211) (416 aa) fasta scores: E(): 0.3,23.7% id in 215 aa.
      
0.773
YPO1063
Similar to Vibrio cholerae cytochrome C554 VC2241 TR:Q9KPX1 (EMBL:AE004296) (107 aa) fasta scores: E(): 1.6e-14, 50.5% id in 105 aa, and to Shewanella violacea soluble cytochrome CB CytCB TR:Q9RHJ5 (EMBL:AB032405) (206 aa) fasta scores: E(): 9.1e-10, 37.7% id in 106 aa, and to Pseudomonas aeruginosa cytochrome C4 precursor PA5490 TR:AAG08875 (EMBL:AE004961) (201 aa) fasta scores: E(): 2.5e-09, 40.4% id in 104 aa.
   
 0.704
YPO1948
Putative cytochrome; Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC58 (EMBL:AL031866) (104 aa) fasta scores: E(): 0, 100.0% id in 103 aa. Similar to Desulfovibrio vulgaris cytochrome c-553 precursor Cyf SW:C553_DESVH (P04032) (103 aa) fasta scores: E(): 0.0048, 29.8% id in 104 aa.
   
 0.704
dadA
D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids.
   
 0.670
solA
Putative sarcosine oxidase; Catalyzes the oxidative demethylation of N-methyl-L- tryptophan; Belongs to the MSOX/MTOX family. MTOX subfamily.
   
 0.670
mnmC
Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.
   
 0.670
YPO1784
Similar to Escherichia coli copper resistance protein C precursor PcoC SW:COPC_ECOLI (Q47454) (126 aa) fasta scores: E(): 4.7e-09, 36.6% id in 123 aa, and to Escherichia coli hypothetical 13.4 kDa protein in pphA-holE intergenic region precursor protein YobA SW:YOBA_ECOLI (P76279) (124 aa) fasta scores: E(): 2.8e-21, 50.8% id in 122 aa.
    
   0.656
ftsH
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
    
   0.591
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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