STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO2000Putative two-component system sensor protein; Member of a two-component regulatory system. (463 aa)    
Predicted Functional Partners:
copR
Similar to Pseudomonas syringae transcriptional activator protein CopR SW:COPR_PSESM (Q02540) (227 aa) fasta scores: E(): 0, 60.8% id in 227 aa, and to Burkholderia pseudomallei transcriptional activator protein IrlR SW:IRLR_BURPS (O31395) (229 aa) fasta scores: E(): 0,57.6% id in 224 aa.
 
 0.983
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
 
 0.953
barA
Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa.
 
0.936
YPO3965
Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa.
 
 0.928
YPO3009
Similar to Streptococcus pneumoniae response regulator Rr02 TR:Q9S1K0 (EMBL:AJ006392) (234 aa) fasta scores: E(): 0, 41.5% id in 234 aa, and to to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP SW:PHOP_BACSU (P13792) (240 aa) fasta scores: E(): 0, 43.7% id in 231 aa.
 
 0.879
YPO3958
Similar to Escherichia coli transcriptional regulatory protein OmpR SW:OMPR_ECOLI (P03025) (239 aa) fasta scores: E(): 9.6e-27, 37.1% id in 237 aa, and to Zymomonas mobilis aerobic respiration control protein ArcA TR:Q9X3W0 (EMBL:AF088896) (241 aa) fasta scores: E(): 8.5e-30, 39.2% id in 240 aa.
 
 0.873
basR
Two-component system response regulator; Similar to Escherichia coli transcriptional regulatory protein BasR or PmrA SW:BASR_ECOLI (P30843) (222 aa) fasta scores: E(): 0, 56.4% id in 218 aa, and to Salmonella typhimurium transcriptional regulatory protein BasR or PmrA SW:BASR_SALTY (P36556) (222 aa) fasta scores: E(): 0, 56.4% id in 218 aa.
 
 0.861
cpxR
Similar to Escherichia coli two component system response regulatory protein CpxR SW:CPXR_ECOLI (P16244) (232 aa) fasta scores: E(): 0, 89.7% id in 232 aa.
 
 0.858
kmt
Similar to Escherichia coli transcriptional regulatory protein OmpR SW:OMPR_ECOLI (P03025) (239 aa) fasta scores: E(): 0, 98.7% id in 239 aa and to Yersinia enterocolitica OmpR TR:P74982 (EMBL:Y08950) (239 aa) fasta scores: E(): 0, 98.7% id in 239 aa.
 
 0.851
blrA
Putative response regulator; Similar to Aeromonas jandaei beta-lactamase production response regulator protein BlrA TR:P97015 (EMBL:U67069) (223 aa) fasta scores: E(): 0, 60.3% id in 229 aa, and to Escherichia coli transcriptional regulatory protein CreB SW:CREB_ECOLI (P08368) (229 aa) fasta scores: E(): 0, 59.4% id in 229 aa. Probable response regulator protein of two-component regulatory system.
 
 0.836
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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