STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
copRSimilar to Pseudomonas syringae transcriptional activator protein CopR SW:COPR_PSESM (Q02540) (227 aa) fasta scores: E(): 0, 60.8% id in 227 aa, and to Burkholderia pseudomallei transcriptional activator protein IrlR SW:IRLR_BURPS (O31395) (229 aa) fasta scores: E(): 0,57.6% id in 224 aa. (230 aa)    
Predicted Functional Partners:
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
0.992
YPO2000
Putative two-component system sensor protein; Member of a two-component regulatory system.
 
 0.983
barA
Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa.
 
 0.977
YPO3965
Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa.
 
 0.942
YPO3008
Putative two-component sensor histidine kinase; Similar to Escherichia coli sensor protein RcsC SW:RCSC_ECOLI (P14376) (933 aa) fasta scores: E(): 1.2e-17,35.1% id in 231 aa, and to Streptococcus pneumoniae histidine kinase PnpS TR:Q9X4S9 (EMBL:AF118229) (422 aa) fasta scores: E(): 1.6e-21, 34.3% id in 251 aa.
 0.889
YPO0256
Two-component sensor/regulator; Similar to Salmonella typhimurium pathogenicity island regulator gene SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 46.5% id in 826 aa and to Vibrio cholerae sensory box sensor histidine kinase/response regulator VieS VC1653 TR:Q9KRI8 (EMBL:AE004243) (1146 aa) fasta scores: E(): 0, 30.4% id in 559 aa. This CDS carries both the sensor and response regulator domains.
 
0.874
nuoD
NADH dehydrogenase I chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
    
   0.872
rcsC
Two component sensor kinase/response regulator protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
0.868
basS
Similar to Escherichia coli sensor protein BasS or PmrB SW:BASS_ECOLI (P30844) (363 aa) fasta scores: E(): 0,49.7% id in 354 aa, and to Salmonella typhimurium sensor protein BasS or PmrB or ParB SW:BASS_SALTY (P36557) (356 aa) fasta scores: E(): 0, 50.4% id in 349 aa.
 
 0.868
cpxA
Similar to Escherichia coli two component sensor kinase, CpxA SW:CPXA_ECOLI (P08336) (457 aa) fasta scores: E(): 0, 80.8% id in 454 aa.
 
 0.853
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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