Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
YPO2007Putative esterase; Weak similarity with the C-terminal regions of Pseudomonas sp lipase LipP TR:O52270 (EMBL:AF034088) (308 aa) fasta scores: E(): 7.2e-05, 27.3% id in 242 aa, and Acinetobacter calcoaceticus carboxylesterase EstA TR:Q60123 (EMBL:X74839) (356 aa) fasta scores: E(): 0.0078, 22.3% id in 251 aa. (276 aa)    
Predicted Functional Partners:
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 0.886
nuoD
NADH dehydrogenase I chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
    
   0.886
nuoF
NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
    
  0.803
YPO2008
Putative rhodanese-like protein; Similar to an internal region of Bacillus halodurans hypothetical protein BH2092 TR:Q9KB42 (EMBL:AP001514) (162 aa) fasta scores: E(): 1.4e-17, 44.5% id in 119 aa, and to the C-terminal region of Vibrio cholerae hypothetical protein VCA1053 TR:Q9KKP9 (EMBL:AE004431) (166 aa) fasta scores: E(): 9.7e-12, 31.0% id in 116 aa.
 
    0.801
nuoE
Similar to Escherichia coli NADH dehydrogenase I chain E NuoE SW:NUOE_ECOLI (P33601) (166 aa) fasta scores: E(): 0, 89.1% id in 156 aa, and to Salmonella typhimurium NADH dehydrogenase I chain E NuoE SW:NUOE_SALTY (P33903) (166 aa) fasta scores: E(): 0, 89.7% id in 156 aa.
    
  0.785
YPO2006
Hypothetical protein; No significant database hits.
       0.777
nifJ
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa.
  
   0.764
nuoG
NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
    
 
 0.752
YPO3991
Putative insulinase family protease; Similar to an internal region of Pisum sativum metalloendopeptidase TR:Q40983 (EMBL:U25111) (1259 aa) fasta scores: E(): 0.00029, 20.4% id in 446 aa, and the full length to Escherichia coli protein YhjJ SW:YHJJ_ECOLI (P37648) (498 aa) fasta scores: E(): 0, 60.6% id in 498 aa.
    
 
 0.744
nuoB
NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
    
   0.709
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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