Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
YPO2008Putative rhodanese-like protein; Similar to an internal region of Bacillus halodurans hypothetical protein BH2092 TR:Q9KB42 (EMBL:AP001514) (162 aa) fasta scores: E(): 1.4e-17, 44.5% id in 119 aa, and to the C-terminal region of Vibrio cholerae hypothetical protein VCA1053 TR:Q9KKP9 (EMBL:AE004431) (166 aa) fasta scores: E(): 9.7e-12, 31.0% id in 116 aa. (132 aa)    
Predicted Functional Partners:
YPO2007
Putative esterase; Weak similarity with the C-terminal regions of Pseudomonas sp lipase LipP TR:O52270 (EMBL:AF034088) (308 aa) fasta scores: E(): 7.2e-05, 27.3% id in 242 aa, and Acinetobacter calcoaceticus carboxylesterase EstA TR:Q60123 (EMBL:X74839) (356 aa) fasta scores: E(): 0.0078, 22.3% id in 251 aa.
 
    0.801
YPO2006
Hypothetical protein; No significant database hits.
       0.795
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
    
   0.683
neaA
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.676
YPO1955
Putative acetyltransferase; Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC61 (EMBL:AL031866) (299 aa) fasta scores: E(): 0, 100.0% id in 299 aa. Similar to Saccharomyces cerevisiae hypothetical protein Yir042C SW:YIW2_YEAST (P40586) (236 aa) fasta scores: E(): 0, 42.6% id in 230 aa.
      0.668
rplQ
Similar to Escherichia coli 50S ribosomal protein L17 RplQ SW:RL17_ECOLI (P02416) (127 aa) fasta scores: E(): 0, 94.5% id in 127 aa.
   
   0.667
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.657
relC
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
   0.601
sodB
Superoxide dismutase [Fe]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.591
sodA
Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.591
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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