STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO2020Similar to Salmonella typhimurium hypothetical protein YchA TR:Q9XCQ1 (EMBL:AF134855) (269 aa) fasta scores: E(): 0, 63.6% id in 269 aa, and to Escherichia coli hypothetical protein YchA SW:YCHA_ECOLI (P20101) (269 aa) fasta scores: E(): 0, 61.7% id in 269 aa. The S. typhimurium protein has been shown to contribute to Salmonella pathogenicity island 1 (SPI1) gene transcription. (269 aa)    
Predicted Functional Partners:
YPO2019
Putative membrane protein; Similar to Salmonella typhimurium hypothetical protein TR:Q9XCQ2 (EMBL:AF134855) (129 aa) fasta scores: E(): 4.6e-23, 56.3% id in 126 aa, and to Escherichia coli hypothetical protein TR:Q46755 (EMBL:U18555) (130 aa) fasta scores: E(): 3.6e-19, 50.8% id in 120 aa. The S. typhimurium protein has been shown to contribute to Salmonella pathogenicity island 1 (SPI1) gene transcription.
  
  
 0.851
rcsF
Putative lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
    0.659
prmC
Putative protoporphyrinogen oxidase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
  
    0.651
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.646
YPO1437
Conserved hypothetical protein; Similar to Haemophilus influenzae DNA transformation protein TfoX SW:TFOX_HAEIN (P43779) (217 aa) fasta scores: E(): 5.5e-05, 27.9% id in 183 aa, and to Escherichia coli hypothetical protein YccR SW:YCCR_ECOLI (P75869) (209 aa) fasta scores: E(): 4.2e-27, 44.6% id in 195 aa. TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes in Haemophilus influenzae.
  
     0.635
kdsA
Similar to Escherichia coli 2-dehydro-3-deoxyphosphooctonate aldolase KdsA SW:KDSA_ECOLI (P17579) (284 aa) fasta scores: E(): 0, 90.1% id in 284 aa, and to Pasteurella haemolytica 2-dehydro-3-deoxyphosphooctonate aldolase KdsA SW:KDSA_PASHA (P95514) (284 aa) fasta scores: E(): 0, 80.3% id in 284 aa; Belongs to the KdsA family.
  
    0.600
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
    0.581
dapX
Lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
    0.581
yacC
Putative exported protein; Similar to Escherichia coli hypothetical 12.8 kDa protein in speE-gcd intergenic region precursor YacC SW:YACC_ECOLI (P23838) (115 aa) fasta scores: E(): 8.1e-33,71.2% id in 111 aa, and to Klebsiella pneumoniae pullulanase secretion protein PulS precursor SW:PULS_KLEPN (P20440) (125 aa) fasta scores: E(): 0.0052, 28.6% id in 105 aa, and to Erwinia chrysanthemi OutS protein precursor SW:OUTS_ERWCH (Q01567) (133 aa) fasta scores: E(): 0.0055,31.3% id in 96 aa.
  
    0.543
YPO0911
Putative exported protein; Similar to Escherichia coli hypothetical protein YgfB SW:YGFB_ECOLI (P25533) (194 aa) fasta scores: E(): 0,66.7% id in 192 aa, and to Haemophilus influenzae hypothetical protein HI0817 SW:YGFB_HAEIN (P44882) (182 aa) fasta scores: E(): 8.9e-29, 43.9% id in 187 aa; Belongs to the UPF0149 family.
  
    0.534
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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