STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argSSimilar to Escherichia coli arginyl-tRNA synthetase ArgS SW:SYR_ECOLI (P11875) (577 aa) fasta scores: E(): 0,82.8% id in 577 aa, and to Vibrio cholerae arginyl-tRNA synthetase VC2074 TR:Q9KQC6 (EMBL:AE004281) (599 aa) fasta scores: E(): 0, 71.4% id in 577 aa. (576 aa)    
Predicted Functional Partners:
drpA
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
 0.985
b0026
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
  
 0.982
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 0.973
leuS
Similar to Escherichia coli leucyl-tRNA synthetase LeuS SW:SYL_ECOLI (P07813) (860 aa) fasta scores: E(): 0,84.8% id in 860 aa, and to Vibrio cholerae leucyl-tRNA synthetase VC0956 TR:Q9KTE6 (EMBL:AE004177) (894 aa) fasta scores: E(): 0, 74.5% id in 858 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.958
guaA
Putative GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.946
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
 0.937
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
 
  
 0.930
asuD
Similar to Escherichia coli lysyl-tRNA synthetase LysS SW:SYK1_ECOLI (P13030) (504 aa) fasta scores: E(): 0,85.9% id in 504 aa, and to Haemophilus influenzae lysyl-tRNA synthetase LysS SW:SYK_HAEIN (P43825) (502 aa) fasta scores: E(): 0, 68.5% id in 504 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.924
glnS
Similar to Escherichia coli glutaminyl-tRNA synthetase GlnS SW:SYQ_ECOLI (P00962) (553 aa) fasta scores: E(): 0, 87.2% id in 549 aa, and to Vibrio cholerae glutaminyl-tRNA synthetase GlnS TR:Q9KTA6 (EMBL:AE004181) (556 aa) fasta scores: E(): 0, 81.1% id in 551 aa.
  
 0.924
YPO2434
Similar to Caulobacter crescentus hypothetical protein CC0128 TR:Q9ABU2 (EMBL:AE005687) (66 aa) fasta scores: E(): 6.5e-05, 38.983% id in 59 aa, and to the C-terminal region of Rhizobium loti hypothetical protein MLL6859 TR:BAB53070 (EMBL:AP003010) (109 aa) fasta scores: E(): 0.0025, 34.783% id in 69 aa.
  
 0.916
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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