Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
btuCPuative vitamin B12 transport system permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (335 aa)    
Predicted Functional Partners:
btuD
Putative vitamin B12 transport ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
 
 
 0.999
btuF
Putative priplasmic metal binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
 
 0.999
fhuC
Similar to Escherichia coli ferrichrome transport ATP-binding protein FhuC SW:FHUC_ECOLI (P07821) (265 aa) fasta scores: E(): 0, 80.8% id in 260 aa, and to Rhizobium leguminosarum FhuC TR:O86461 (EMBL:AJ007906) (268 aa) fasta scores: E(): 0, 51.6% id in 254 aa.
 
  
 0.869
YPO1345
Similar to Escherichia coli ferrichrome transport ATP-binding protein FhuC SW:FHUC_ECOLI (P07821) (265 aa) fasta scores: E(): 2.7e-22, 32.8% id in 259 aa, and to Streptomyces coelicolor Fe uptake system permease FtrE TR:CAC14366 (EMBL:AL445963) (272 aa) fasta scores: E(): 8.8e-22, 34.2% id in 260 aa.
 
  
 0.851
YPO1533
Putative iron-siderophore transport system,ATP-binding component; Similar to Vibrio cholerae ferric vibriobactin ABC transporter, ATP-binding protein vc0779 TR:Q9KTV8 (EMBL:AE004163) (279 aa) fasta scores: E(): 0, 55.9% id in 263 aa, and to Streptomyces coelicolor putative iron-siderophore uptake system ATP-binding component sci51.25C TR:Q9S215 (EMBL:AL109848) (301 aa) fasta scores: E(): 0, 57.2% id in 264 aa.
 
  
 0.825
YPO1310
Putative periplasmic substrate-binding transport protein; Similar to Methanococcus jannaschii hypothetical protein MJ0085 SW:Y085_METJA (Q57550) (373 aa) fasta scores: E(): 1.6e-10, 26.7% id in 352 aa, and to Archaeoglobus fulgidus possible iron (III) ABC transporter,ATP-binding protein (hemV-2) AF0432 TR:O29817 (EMBL:AE001075) (366 aa) fasta scores: E(): 2.3e-09, 27.9% id in 344 aa.
 
 
  0.820
YPO1343
Putative periplasmic binding protein; Similar to Vibrio cholerae vibriobactin and enterobactin periplasmic binding protein ViuP TR:Q9RCF6 (EMBL:U52150) (325 aa) fasta scores: E(): 0.00051, 25.9% id in 259 aa, and to Thermotoga maritima possible iron(III) ABC transporter, periplasmic iron-binding protein TM0189 TR:Q9WY32 (EMBL:AE001704) (358 aa) fasta scores: E(): 0.0025, 24.9% id in 374 aa.
 
 
  0.817
hmuT
Hemin-binding periplasmic protein; Part of the binding-protein-dependent transport system for hemin.
  
   
 0.806
YPO0955
Hypothetical protein; Weakly similar to internal regions of Pseudomonas aeruginosa periplasmic binding protein PhuT TR:O68879 (EMBL:AF055999) (297 aa) fasta scores: E(): 0.0054, 27.7% id in 256 aa, and Pyrococcus horikoshii hypothetical protein PH1237 TR:O58946 (EMBL:AP000005) (366 aa) fasta scores: E(): 0.0047, 26.5% id in 283 aa.
 
 
  0.794
hmuV
Hemin transport system ATP-binding protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (Probable); Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
  
   
 0.789
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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