STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yapCPutaive autotransporter protein; Previously sequenced as Yersinia pestis putative autotransporter protein YapC TR:CAC14222 (EMBL:AJ277626) (638 aa) fasta scores: E(): 0, 100.0% id in 638 aa, Similar to Escherichia coli invasion locus B protein TibA TR:Q9XD84 (EMBL:AF109215) (989 aa) fasta scores: E(): 0, 31.7% id in 666 aa. (638 aa)    
Predicted Functional Partners:
YPO1672
Conserved hypothetical protein; Similar to Bordetella pertussis BapA protein TR:CAC14165 (EMBL:AJ277632) (903 aa) fasta scores: E(): 0,32.6% id in 915 aa, to Escherichia coli YchA protein TR:Q9JMS3 (EMBL:AP001918) (1371 aa) fasta scores: E(): 8.4e-25, 24.7% id in 1300 aa, and to the previously sequenced Yersinia pestis YapE protein TR:CAC14224 (EMBL:AJ277628) (1072 aa) fasta scores: E(): 1.5e-18, 23.9% id in 1160 aa. Similar to YPO0765 (82.4% identity in 1206 aa overlap) and YPO0309 (81.1% identity in 1199 aa overlap).
  
    0.639
YPO0863
Putative lipoprotein; Similar to Escherichia coli hypothetical lipoprotein YaeF SW:YAEF_ECOLI (P37056) (274 aa) fasta scores: E(): 0,43.1% id in 253 aa.
  
     0.557
YPO0899
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCD6.09C TR:Q9KZZ5 (EMBL:AL353815) (169 aa) fasta scores: E(): 3e-18, 40.6% id in 160 aa.
  
     0.492
fliH
Similar to Vibrio parahaemolyticus polar flagellar assembly protein FliH TR:Q9Z6G6 (EMBL:AF069392) (266 aa) fasta scores: E(): 9e-11, 24.8% id in 210 aa, and to Escherichia coli flagellar assembly protein FliH SW:FLIH_ECOLI (P31068) (228 aa) fasta scores: E(): 7.5e-09,22.5% id in 209 aa.
  
    0.487
YPO0736
Putative regulatory protein; N-terminus similar to the N-terminus regions of Photobacterium profundum protein required for pressure-responsive gene expression ToxR TR:O66013 (EMBL:U77060) (290 aa) fasta scores: E(): 1.6e-06, 30.0% id in 150 aa, and to Vibrio fischeri transmembrane transcriptional activator ToxR TR:Q56689 (EMBL:L29053) (316 aa) fasta scores: E(): 2.1e-06, 28.5% id in 172 aa.
  
    0.487
YPO2873
Similar to Vibrio cholerae hypothetical protein VC0765 TR:Q9KTW5 (EMBL:AE004162) (77 aa) fasta scores: E(): 5e-09, 36.5% id in 74 aa, and to C-terminal region of Escherichia coli hypothetical protein YfgJ SW:YFGJ_ECOLI (P76575) (83 aa) fasta scores: E(): 4.8e-16, 64.1% id in 64 aa.
  
    0.468
YPO4041
Similar to Proteus mirabilis fimbrial chaperone MrpD TR:Q51905 (EMBL:Z32686) (252 aa) fasta scores: E(): 0,44.9% id in 247 aa, and to Escherichia coli hypothetical fimbrial chaperone YbgP SW:YBGP_ECOLI (P75749) (242 aa) fasta scores: E(): 0, 47.1% id in 238 aa.
  
    0.466
YPO0698
Similar to Escherichia coli outer membrane usher protein PapC SW:PAPC_ECOLI (P07110) (836 aa) fasta scores: E(): 0, 48.4% id in 834 aa, and to Proteus mirabilis outer membrane usher protein MrpC TR:Q51904 (EMBL:Z32686) (871 aa) fasta scores: E(): 0, 45.8% id in 825 aa.
  
    0.465
yapG
Previously sequenced, Yersinia pestis putative autotransporter protein YapG TR:CAC14226 (EMBL:AJ277630). Similar to Salmonella typhimurium pathogenicity island (SPI-3) protein MisL TR:Q9Z625 (EMBL:AF106566) (955 aa) fasta scores: E(): 0, 29.7% id in 966 aa.
  
   
0.464
YPO0762
Similar to Pseudomonas aeruginosa hypothetical protein PA2684 TR:AAG06072 (EMBL:AE004696) (1317 aa) fasta scores: E(): 3.9e-30, 27.3% id in 1251 aa, and to Escherichia coli putative rhs protein RhsD SW:RHSD_ECOLI (P16919) (1426 aa) fasta scores: E(): 1e-24, 26.5% id in 1288 aa. The CDS has an extension at the N-terminal end in comparison to other orthologues, possible alternative translational starts.
  
    0.463
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.