STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO2804Hypothetical protein; No significant database hits. (542 aa)    
Predicted Functional Partners:
gidA
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
   
   0.634
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
  
 0.633
flgC
Similar to Escherichia coli flagellar basal-body rod protein FlgC SW:FLGC_ECOLI (P75935) (134 aa) fasta scores: E(): 5.2e-17, 46.1% id in 141 aa, and to Vibrio parahaemolyticus possible flagellar basal-body rod protein LfgC TR:Q56720 (EMBL:U51896) (144 aa) fasta scores: E(): 6.8e-28, 57.0% id in 142 aa.
   
   0.623
fla-4
Similar to Salmonella typhimurium flagellar basal-body rod protein FlgC or FlaW or Fla FIII SW:FLGC_SALTY (P16438) (134 aa) fasta scores: E(): 0, 79.9% id in 134 aa, and to Yersinia enterocolitica flagellar basal-body rod protein FlgC SW:FLGC_YEREN (Q56894) (134 aa) fasta scores: E(): 0, 96.3% id in 134 aa.
   
   0.623
poaA
Bifunctional PutA protein [includes: proline dehydrogenase and delta-1-pyrroline-5-carboxylate; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
   
  0.541
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
    
   0.480
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
    
  0.456
YPO3965
Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa.
   
 0.438
manC
Similar to Yersinia pseudotuberculosis mannose-1-phosphate guanylyltransferase ManC TR:Q9RCB1 (EMBL:AJ251712) (468 aa) fasta scores: E(): 0, 99.8% id in 468 aa, and to Yersinia enterocolitica mannose-1-phosphate guanylyltransferase RfbM or ManC TR:Q56874 (EMBL:U46859) (465 aa) fasta scores: E(): 0, 80.7% id in 462 aa, and identical to the previously sequenced Yersinia pestis mannose-1-phosphate guanylyltransferase ManC TR:Q9RCC5 (EMBL:AJ251713) (468 aa) fasta scores: E(): 0, 100.0% id in 468 aa; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.429
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.423
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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