STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fsrBFlavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (396 aa)    
Predicted Functional Partners:
ytfE
Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.
  
  
 0.969
nsrR
Conserved hypothetical protein; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.
 
  
 0.898
nirB
Nitrite reductase; Similar to Escherichia coli nitrite reductase NirB SW:NIRB_ECOLI (P08201) (847 aa) fasta scores: E(): 0, 82.7% id in 849 aa; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.895
hcp
Putative prismane protein homologue; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.892
tehB
Previously sequenced as Yersinia pestis probable tellurite resistance protein TehB TR:Q9ZC59 (EMBL:AL031866) (295 aa) fasta scores: E(): 0, 100.0% id in 295 aa. Similar to Streptococcus pneumoniae tellurite resistance protein TehB TR:Q9X3Q7 (EMBL:AF079807) (286 aa) fasta scores: E(): 0, 56.2% id in 283 aa.
  
  
 0.866
YPO2492
Putative dioxygenase beta subunit; Converts carnitine to trimethylamine and malic semialdehyde.
 
 
 0.839
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
  
 
 0.794
barA
Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa.
 
 
 0.757
ascD
Cdp-6-deoxy-delta-3,4-glucoseen reductase; Participates in the conversion of CDP-6-deoxy-D-glycero-L- threo-4-hexulose to 3,6-dideoxy-D-glycero-D-glycero-4-hexulose together with CDP-6-deoxy-D-glycero-L-threo-4-hexulose-3-dehydrase (E1) in two consecutive steps. The detailed mechanism of E3 is not yet resolved (By similarity).
 
 
0.726
YPO2515
Putative chemotactic transducer; Similar to an internal region of Pseudomonas aeruginosa chemotactic transducer PctB TR:O32443 (EMBL:D86947) (629 aa) fasta scores: E(): 3.3e-14, 27.3% id in 395 aa, and to Campylobacter jejuni putative MCP-type signal transduction protein CJ1110C TR:Q9PNI4 (EMBL:AL139077) (429 aa) fasta scores: E(): 0, 36.4% id in 407 aa. The CDS appears to be truncated at the N-terminus in comparison to the Campylobacter jejuni protein and other homologues. Insertion of an IS100 element directly upstream has probably disrupted the promoter of this CDS. Effect on the fu [...]
  
 
 0.703
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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