STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nanKPutative sugar kinase; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (290 aa)    
Predicted Functional Partners:
nanE
Putative outer membrane protein (pseudogene); Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 0.998
nanA
Similar to Escherichia coli N-acetylneuraminate lyase subunit NanA or Npl SW:NPL_ECOLI (P06995) (296 aa) fasta scores: E(): 1.7e-16, 29.1% id in 265 aa, and to Vibrio cholerae N-acetylneuraminate lyase, putative VC1776 TR:Q9KR67 (EMBL:AE004255) (298 aa) fasta scores: E(): 0,75.1% id in 293 aa.
 
 
 0.993
nagE
Similar to Escherichia coli PTS system,N-acetylglucosamine-specific IIABC component NagE SW:PTAA_ECOLI (P09323) (648 aa) fasta scores: E(): 0, 52.6% id in 683 aa, and to Vibrio furnissii PTS permease for N-acetylglucosamine and glucose NagE TR:P96161 (EMBL:U65014) (496 aa) fasta scores: E(): 0, 69.9% id in 495 aa.
  
 0.972
glcA
Similar to Escherichia coli PTS system,glucose-specific IIBC component Ptsg or Glca or UmG SW:PTGB_ECOLI (P05053) (477 aa) fasta scores: E(): 0, 90.4% id in 477 aa, and to Salmonella typhimurium PTS system,glucose-specific IIBC component PtsG SW:PTGB_SALTY (P37439) (477 aa) fasta scores: E(): 0, 88.7% id in 477 aa.
  
 0.958
treB
Similar to Escherichia coli PTS system,trehalose-specific IIBC component TreB SW:PTTB_ECOLI (P36672) (473 aa) fasta scores: E(): 0, 80.5% id in 471 aa,and to Vibrio cholerae PTS system, trehalose-specific IIBC component Vc0910 TR:Q9KTJ2 (EMBL:AE004175) (478 aa) fasta scores: E(): 0, 70.0% id in 474 aa.
  
 0.958
nanT
Putative sugar transporter; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
   
  
 0.851
glmD
Putative glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.787
nagA
Similar to Escherichia coli N-acetylglucosamine-6-phosphate deacetylase NagA SW:NAGA_ECOLI (P15300) (382 aa) fasta scores: E(): 0, 75.1% id in 381 aa, and to Vibrio cholerae N-acetylglucosamine-6-phosphate deacetylase NagA SW:NAGA_VIBCH (O32445) (378 aa) fasta scores: E(): 0, 64.1% id in 376 aa.
 
 
 0.776
YPO2036
Putative transcriptional regulatory protein; N-terminal region is similar to the N-terminus of Bacillus subtilis xylose repressor XylR SW:XYLR_BACSU (P16557) (384 aa) fasta scores: E(): 2.4e-15, 27.7% id in 256 aa. Full length CDS has weak similarity to Rhizobium sp hypothetical protein Y4FQ SW:Y4FQ_RHISN (P55455) (392 aa) fasta scores: E(): 1.4e-27, 30.1% id in 366 aa.
 
 
 0.765
YPO3019
Similar to Escherichia coli hypothetical protein YhcH SW:YHCH_ECOLI (P45424) (154 aa) fasta scores: E(): 9.6e-22, 47.6% id in 143 aa, and to Haemophilus influenzae hypothetical protein HI0227 SW:YHCH_HAEIN (P44583) (155 aa) fasta scores: E(): 2.1e-21, 48.3% id in 151 aa.
  
 
 0.759
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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