STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybcIPutative membrane protein; Similar to Escherichia coli hypothetical 19.5 kDa protein in cysS-folD intergenic region YbcI SW:YBCI_ECOLI (P45570) (173 aa) fasta scores: E(): 0, 72.4% id in 174 aa,and to Pseudomonas aeruginosa hypothetical protein PA4962 TR:AAG08347 (EMBL:AE004909) (178 aa) fasta scores: E(): 1.2e-29, 48.0% id in 177 aa. (182 aa)    
Predicted Functional Partners:
YPO0112
Similar to Escherichia coli hypothetical protein YiaA SW:YIAA_ECOLI (P11287) (145 aa) fasta scores: E(): 0,62.5% id in 136 aa.
  
    0.695
ynbD
Putative dual specificity phosphatase; Similar to Escherichia coli hypothetical protein YnbD SW:YNBD_ECOLI (P76093) (430 aa) fasta scores: E(): 0,49.6% id in 415 aa, and to Pseudomonas aeruginosa hypothetical protein PA2539 TR:AAG05927 (EMBL:AE004681) (437 aa) fasta scores: E(): 0, 44.0% id in 432 aa.
 
    0.494
dmsC-2
Similar to Escherichia coli anaerobic dimethyl sulfoxide reductase chain C DmsC SW:DMSC_ECOLI (P18777) (287 aa) fasta scores: E(): 0, 66.7% id in 285 aa, and identical to the previously sequenced to Yersinia pestis dimethyl sulfoxide reductase subunit C DmsC TR:Q9X6B4 (EMBL:AF135170) (286 aa) fasta scores: E(): 0, 100.0% id in 286 aa.
  
    0.460
YPO3028
Putative autotransporter; Similar to Escherichia coli TibA TR:Q9XD84 (EMBL:AF109215) (989 aa) fasta scores: E(): 0, 32.8% id in 798 aa, and to Yersinia pestis putative autotransporter protein YapC TR:CAC14222 (EMBL:AJ277626) (638 aa) fasta scores: E(): 0, 38.9% id in 455 aa.
  
    0.439
creC
Similar to Myxococcus xanthus developmental histidine kinase sensor SasS TR:O52223 (EMBL:AF029787) (497 aa) fasta scores: E(): 1.4e-23, 28.2% id in 485 aa, and to Escherichia coli sensor protein CreC SW:CREC_ECOLI (P08401) (474 aa) fasta scores: E(): 0, 58.3% id in 470 aa. Probable sensor kinase protein of two-component regulatory system.
  
     0.438
creD
Similar to Escherichia coli inner membrane protein CreD SW:CRED_ECOLI (P08369) (450 aa) fasta scores: E(): 0,47.1% id in 429 aa, and to Aeromonas hydrophila putative inner membrane protein BlrD TR:Q9KGR5 (EMBL:AJ276632) (449 aa) fasta scores: E(): 0, 46.9% id in 452 aa.
  
     0.420
YPO2856
Putative diacylglycerol kinase; Probably phosphorylates lipids; the in vivo substrate is unknown.
 
    0.420
dmsC
Similar to Escherichia coli anaerobic dimethyl sulfoxide reductase chain C protein DmsC SW:DMSC_ECOLI (P18777) (287 aa) fasta scores: E(): 1.1e-10, 32.6% id in 273 aa, and to Yersinia pestis probable dimethyl sulfoxide reductase subunit C DmsC TR:Q9X6B4 (EMBL:AF135170) (286 aa) fasta scores: E(): 4.7e-12, 33.7% id in 276 aa.
  
    0.410
YPO3044
Hypothetical protein; Weakly similar to internal regions of Myrothecium roridum trichodiene synthase Tri5 SW:TRI5_MYRRO (O13489) (385 aa) fasta scores: E(): 2.1, 26.0% id in 150 aa, and to Arabidopsis thaliana hypothetical protein TR:BAB09824 (EMBL:AB006708) (277 aa) fasta scores: E(): 0.99, 32.5% id in 120 aa.
       0.409
pla2
Putative outer membrane-associated protease; Similar to virulence associated proteases eg. Yersinia pestis plasmid pPCP1 coagulase/fibrinolysin precursor Pla SW:COLY_YERPE (P17811) (312 aa) fasta scores: E(): 0, 43.5% id in 313 aa, and to Salmonella typhimurium outer membrane protease E precursor PgtE or PrtA SW:PGTE_SALTY (P06185) (296 aa) fasta scores: E(): 0, 47.6% id in 248 aa, and to Escherichia coli protease VII precursor OmpT SW:OMPT_ECOLI (P09169) (317 aa) fasta scores: E(): 0, 40.0% id in 290 aa, and to Shigella flexneri 2a icsa-cleaving protease IcsP TR:O33641 (EMBL:AF001633) [...]
  
    0.403
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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