STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyoCSimilar to Escherichia coli cytochrome O ubiquinol oxidase subunit III CyoC SW:CYOC_ECOLI (P18402) (204 aa) fasta scores: E(): 0, 75.1% id in 205 aa, and to Pseudomonas putida cytochrome O ubiquinol oxidase subunit III CyoC SW:CYOC_PSEPU (Q9WWR3) (207 aa) fasta scores: E(): 0, 64.6% id in 209 aa. (204 aa)    
Predicted Functional Partners:
cyoA
Similar to Escherichia coli ubiquinol oxidase polypeptide II precursor CyoA SW:CYOA_ECOLI (P18400) (315 aa) fasta scores: E(): 0, 66.9% id in 317 aa, and to Pseudomonas putida ubiquinol oxidase polypeptide II precursor CyoA SW:CYOA_PSEPU (Q9WWR1) (314 aa) fasta scores: E(): 0, 57.5% id in 320 aa.
 
 0.999
cyoB
Similar to Escherichia coli ubiquinol oxidase polypeptide I CyoB SW:CYOB_ECOLI (P18401) (663 aa) fasta scores: E(): 0, 84.3% id in 663 aa, and to Pseudomonas aeruginosa cytochrome O ubiquinol oxidase subunit I CyoB or Pa1318 TR:AAG04707 (EMBL:AE004561) (658 aa) fasta scores: E(): 0, 67.7% id in 656 aa; Belongs to the heme-copper respiratory oxidase family.
 0.999
cyoD
Similar to Escherichia coli cytochrome O ubiquinol oxidase protein CyoD SW:CYOD_ECOLI (P18403) (109 aa) fasta scores: E(): 2.7e-25, 65.1% id in 109 aa, and to Pseudomonas aeruginosa cytochrome O ubiquinol oxidase subunit IV CyoD or Pa1320 TR:AAG04709 (EMBL:AE004561) (111 aa) fasta scores: E(): 1.1e-19, 57.4% id in 108 aa.
 
 0.999
cyoE
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 
 0.999
atpB
ATP synthase subunit B protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
   
 
 0.992
nuoM
NADH dehydrogenase I chain M; Similar to Escherichia coli SW:NUOM_ECOLI (P31978) (509 aa) fasta scores: E(): 0, 85.6% id in 513 aa, and to Pseudomonas aeruginosa NADH dehydrogenase I chain M NuoM TR:AAG06036 (EMBL:AE004693) (509 aa) fasta scores: E(): 0,74.9% id in 502 aa.
   
 0.990
nuoH
NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
 0.990
nuoN
NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
   
 0.985
nuoD
NADH dehydrogenase I chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.981
nuoA
NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
   
 0.979
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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