STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)    
Predicted Functional Partners:
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
poaA
Bifunctional PutA protein [includes: proline dehydrogenase and delta-1-pyrroline-5-carboxylate; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
    
 0.965
proC
Putative pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.829
aspB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 87.4% id in 1497 aa, and to Vibrio cholerae glutamate synthase, large subunit Vc2376 TR:Q9KPJ1 (EMBL:AE004308) (1487 aa) fasta scores: E(): 0, 73.7% id in 1488 aa.
 
 
 0.747
argM
Succinylornithine aminotransferase; Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
 
 
 0.723
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
  
 0.650
pepD
Similar to Escherichia coli aminoacyl-histidine dipeptidase PepD or PepH SW:PEPD_ECOLI (P15288) (484 aa) fasta scores: E(): 0, 78.3% id in 484 aa, and to Haemophilus influenzae aminoacyl-histidine dipeptidase PepD or HI0675 SW:PEPD_HAEIN (P44817) (483 aa) fasta scores: E(): 0, 53.6% id in 485 aa.
      
 0.646
potG
Putrescine transport ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
   
  
 0.574
pepN
Similar to Escherichia coli aminopeptidase N PepN SW:AMPN_ECOLI (P04825) (869 aa) fasta scores: E(): 0, 77.2% id in 869 aa, and to Vibrio cholerae aminopeptidase N VC1494 TR:Q9KRY9 (EMBL:AE004227) (868 aa) fasta scores: E(): 0, 65.1% id in 871 aa.
      
 0.552
glnA
Glutamine synthetase; Highly similar to Escherichia coli glutamine synthetase GlnA SW:GLNA_ECOLI (P06711) (468 aa) fasta scores: E(): 0, 91.5% id in 468 aa.
     
 0.551
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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