STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sgbUSimilar to Escherichia coli putative hexulose-6-phosphate isomerase SgbU SW:SGBU_ECOLI (P37679) (286 aa) fasta scores: E(): 0, 71.5% id in 284 aa, and to Haemophilus influenzae putative hexulose-6-phosphate isomerase SgbU or Hi1026 SW:SGBU_HAEIN (P44990) (286 aa) fasta scores: E(): 0, 63.3% id in 283 aa. (293 aa)    
Predicted Functional Partners:
lyx
Putative L-xylulose kinase; Similar to Escherichia coli cryptic L-xylulose kinase Lyx or LyxK or XylK or SgbK SW:LYXK_ECOLI (P37677) (498 aa) fasta scores: E(): 0, 42.8% id in 495 aa, and to Haemophilus influenzae probable L-xylulose kinase Lyx or LyxK or SgbK or Hi1027 SW:LYXK_HAEIN (P44991) (485 aa) fasta scores: E(): 0, 39.5% id in 499 aa.
 
 
 0.971
araD-2
Similar to Escherichia coli L-ribulose-5-phosphate 4-epimerase AraD SW:ARAD_ECOLI (P08203) (231 aa) fasta scores: E(): 0, 73.6% id in 231 aa, and identical to the previously sequenced Yersinia pestis L-ribulose-phosphate 4-epimerase AraD TR:Q9X6B7 (EMBL:AF135170) (256 aa) fasta scores: E(): 0, 100.0% id in 231 aa. Similar to YPO2230 (69.9% identity in 249 aa overlap).
  
 0.948
araD
Similar to Salmonella typhimurium L-ribulose-5-phosphate 4-epimerase AraD SW:ARAD_SALTY (P06190) (231 aa) fasta scores: E(): 0, 75.8% id in 231 aa,and to Escherichia coli L-ribulose-5-phosphate 4-epimerase AraD SW:ARAD_ECOLI (P08203) (231 aa) fasta scores: E(): 0,74.9% id in 231 aa. CDS is similar to YPO3326 (256 aa) fasta scores: E(): 0, 69.9% identity in 249 aa overlap.
  
 0.921
araB
L-ribulokinase; Similar to Escherichia coli L-ribulokinase AraB SW:KIRI_ECOLI (P08204) (565 aa) fasta scores: E(): 0, 72.2% id in 553 aa, and to Salmonella typhimurium L-ribulokinase AraB SW:KIRI_SALTY (P06188) (569 aa) fasta scores: E(): 0,72.2% id in 551 aa.
    
  0.799
YPO2782
Putative membrane protein; Similar to Bacillus halodurans hypothetical protein BH0223 TR:Q9KG89 (EMBL:AP001507) (432 aa) fasta scores: E(): 0, 39.3% id in 422 aa, and to N-terminal region of Streptomyces coelicolor putative integral membrane protein SCJ21.17C TR:Q9S1Z0 (EMBL:AL109747) (516 aa) fasta scores: E(): 0, 48.2% id in 434 aa.
 
   
 0.693
YPO1236
Putative class II aldolase-family protein; Similar to Escherichia coli hypothetical protein YgbL SW:YGBL_ECOLI (Q46890) (212 aa) fasta scores: E(): 0,57.1% id in 168 aa, and to Escherichia coli L-fuculose phosphate aldolase FucA or FucC or Prd SW:FUCA_ECOLI (P11550) (215 aa) fasta scores: E(): 2.6e-07, 32.7% id in 159 aa.
 
  
 0.656
lsrK
Putative transcriptional regulator (pseudogene); Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
 
 
 0.614
YPO2569
Phosphotransferase enzyme II, A component; Similar to Escherichia coli phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), mannitol permease IIa protein, CmtB SW:PTYA_ECOLI (P32058) (147 aa) fasta scores: E(): 9.8e-18,42.3% id in 137 aa, and to Vibrio cholerae PTS system, IIa component VCA0245 TR:Q9KMS5 (EMBL:AE004364) (168 aa) fasta scores: E(): 1.5e-16, 37.4% id in 147 aa.
 
     0.564
xylB-2
Putative carbohydrate kinase; Similar to Thermoanaerobacter ethanolicus xylulose kinase XylB TR:O30364 (EMBL:AF001974) (500 aa) fasta scores: E(): 0, 40.7% id in 511 aa, and to Bacillus subtilis xylulose kinase XylB SW:XYLB_BACSU (P39211) (499 aa) fasta scores: E(): 0, 36.6% id in 517 aa.
    
 0.482
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
      
 0.448
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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