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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Score
aceFDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (509 aa)    
Predicted Functional Partners:
lpd
Dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase complex; Similar to Escherichia coli dihydrolipoamide dehydrogenase LpdA or Lpd SW:DLDH_ECOLI (P00391) (473 aa) fasta scores: E(): 0, 93.9% id in 473 aa, and to Vibrio cholerae pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase Vc2412 TR:Q9KPF6 (EMBL:AE004311) (475 aa) fasta scores: E(): 0, 86.5% id in 474 aa.
 0.999
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
sucA
Similar to Escherichia coli 2-oxoglutarate dehydrogenase E1 component SucA SW:ODO1_ECOLI (P07015) (933 aa) fasta scores: E(): 0, 87.8% id in 935 aa, and to Vibrio cholerae 2-oxoglutarate dehydrogenase, E1 component VC2087 TR:Q9KQB3 (EMBL:AE004282) (936 aa) fasta scores: E(): 0,73.8% id in 936 aa.
 0.997
YPO3917
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Halobacterium volcanii dihydrolipoamide dehydrogenase Lpd SW:DLDH_HALVO (Q04829) (474 aa) fasta scores: E(): 2.8e-30, 29.2% id in 466 aa, and to Vibrio cholerae class I pyridine nucleotide-disulfide oxidoreductase VC2638 TR:Q9KNU2 (EMBL:AE004330) (484 aa) fasta scores: E(): 0, 75.0% id in 488 aa.
  
 0.994
gltA
Citrate synthase GltA; Similar to Escherichia coli citrate synthase GltA SW:CISY_ECOLI (P00891) (427 aa) fasta scores: E(): 0, 86.7% id in 427 aa, and to Vibrio cholerae citrate synthase VC2092 TR:Q9KQA8 (EMBL:AE004283) (431 aa) fasta scores: E(): 0, 78.0% id in 422 aa.
  
 0.991
b0728
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.987
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.983
nifJ
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa.
  
 0.971
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.955
sth
Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 0.954
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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