Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
cpdBSimilar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB SW:CN16_ECOLI (P08331) (647 aa) fasta scores: E(): 0, 76.0% id in 646 aa, and to Yersinia enterocolitica 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB SW:CN16_YEREN (P53052) (652 aa) fasta scores: E(): 0, 91.3% id in 652 aa; Belongs to the 5'-nucleotidase family. (656 aa)    
Predicted Functional Partners:
YPO2295
Haloacid dehalogenase-like hydrolase family protein; Similar to Vibrio cholerae hypothetical protein VCA0608 TR:Q9KLY3 (EMBL:AE004391) (224 aa) fasta scores: E(): 0, 62.9% id in 224 aa; Similar to Vibrio cholerae hypothetical protein VCA0608 TR:Q9KLY3 (EMBL:AE004391) (224 aa) fasta scores: E(): 0, 62.9% id in 224 aa, and to Escherichia coli hypothetical protein YjjG SW:YJJG_ECOLI (P33999) (225 aa) fasta scores: E(): 0, 56.8% id in 222 aa.
   
 
 0.943
nagD
Similar to Escherichia coli N-acetylglucosamine utilization operon hypothetical protein NagD SW:NAGD_ECOLI (P15302) (250 aa) fasta scores: E(): 0, 86.0% id in 250 aa,and to Streptomyces coelicolor conserved hypothetical protein SCE20.17c TR:Q9RDA8 (EMBL:AL136058) (259 aa) fasta scores: E(): 0, 45.0% id in 249 aa.
  
 
 0.924
surE
Stationary-phase survival protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
     
 0.921
b4384
Similar to Escherichia coli purine nucleoside phosphorylase DeoD SW:DEOD_ECOLI (P09743) (238 aa) fasta scores: E(): 0, 91.1% id in 236 aa, and to Klebsiella pneumoniae purine nucleoside phosphorylase DeoD SW:DEOD_KLEPN (Q59482) (239 aa) fasta scores: E(): 0, 88.7% id in 238 aa.
    
 0.911
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
    
 0.910
pndA
Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.908
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.906
b4390
Similar to Salmonella typhimurium transcriptional regulator NadR SW:NADR_SALTY (P24518) (409 aa) fasta scores: E(): 0, 85.0% id in 406 aa, and to Escherichia coli transcriptional regulator NadR SW:NADR_ECOLI (P27278) (410 aa) fasta scores: E(): 0, 83.7% id in 406 aa.
  
  
 0.905
YPO0141
Similar to Escherichia coli hypothetical protein YrfG SW:YRFG_ECOLI (P45801) (222 aa) fasta scores: E(): 0,67.0% id in 221 aa.
   
 
 0.904
b2066
Uridine kinase; Similar to Escherichia coli uridine kinase SW:URK_ECOLI (P31218) (213 aa) fasta scores: E(): 0, 91.1% id in 213 aa, and to Vibrio cholerae uridine kinase vc1038 TR:Q9KT67 (EMBL:AE004185) (219 aa) fasta scores: E(): 0,75.0% id in 208 aa.
  
 
  0.903
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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