STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yjcDPutative xanthine/uracil permease; Similar to Escherichia coli hypothetical 45.7 kDa protein in soxR-acs intergenic region YjcD SW:YJCD_ECOLI (P32702) (449 aa) fasta scores: E(): 0, 85.0% id in 448 aa,and to Shewanella massilia hypothetical membrane protein TR:O87945 (EMBL:AJ006085) (450 aa) fasta scores: E(): 0,76.0% id in 445 aa. (451 aa)    
Predicted Functional Partners:
purI-2
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.898
yjcE
Putative putative Na(+)/H(+) exchanger protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
 
    0.788
YPO0034
Similar to Escherichia coli putative purine permease YicE SW:YICE_ECOLI (P27432) (463 aa) fasta scores: E(): 0,84.0% id in 462 aa and to Vibrio cholerae xanthine/uracil permease family protein vc2712 TR:Q9KNM0 (EMBL:AE004337) (480 aa) fasta scores: E(): 0, 69.1% id in 450 aa.
 
  
 0.688
yieG
Xanthine/uracil permeases family protein; Similar to Escherichia coli hypothetical protein YieG SW:YIEG_ECOLI (P31466) (445 aa) fasta scores: E(): 0,86.8% id in 432 aa, and to Escherichia coli hypothetical protein YicO or b3664 SW:YICO_ECOLI (P31440) (470 aa) fasta scores: E(): 0, 76.2% id in 445 aa.
  
   
0.681
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.611
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
    0.602
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
  
 0.600
purI
Putative phosphoribosylaminoimidazole synthetase; Similar to Salmonella typhimurium probable 5'-phosphoribosyl-5-aminoimidazole synthetase PurI TR:P74883 (EMBL:U68765) (345 aa) fasta scores: E(): 0,83.5% id in 345 aa, and to Escherichia coli probable phosphoribosylaminoimidazole synthetase PurM TR:AAG14577 (EMBL:AF293164) (350 aa) fasta scores: E(): 0, 82.6% id in 345 aa.
  
    0.597
purD
Similar to Escherichia coli phosphoribosylamine--glycine ligase PurD SW:PUR2_ECOLI (P15640) (429 aa) fasta scores: E(): 0, 80.8% id in 426 aa,and to Salmonella typhimurium phosphoribosylamine--glycine ligase PurD or Stmf1.31 SW:PUR2_SALTY (P26977) (429 aa) fasta scores: E(): 0, 79.6% id in 426 aa.
  
  
 0.584
purC
Similar to Escherichia coli phosphoribosylaminoimidazole-succinocarboxamide synthase PurC SW:PUR7_ECOLI (P21155) (237 aa) fasta scores: E(): 0,86.9% id in 237 aa, and to Pseudomonas aeruginosa phosphoribosylaminoimidazole-succinocarboxamide synthase Purc or Pa1013 TR:AAG04402 (EMBL:AE004533) (236 aa) fasta scores: E(): 0, 72.5% id in 236 aa; Belongs to the SAICAR synthetase family.
  
  
 0.566
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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