STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argESimilar to Escherichia coli acetylornithine deacetylase ArgE SW:ARGE_ECOLI (P23908) (383 aa) fasta scores: E(): 0, 77.5% id in 386 aa, and to Moritella sp 2674 acetylornithinase ArgE TR:Q9K4Z7 (EMBL:AJ252020) (381 aa) fasta scores: E(): 0, 58.4% id in 385 aa; Belongs to the peptidase M20A family. ArgE subfamily. (389 aa)    
Predicted Functional Partners:
argG
Similar to Escherichia coli argininosuccinate synthase ArgG SW:ASSY_ECOLI (P22767) (446 aa) fasta scores: E(): 0, 90.5% id in 440 aa, and to Neisseria meningitidis argininosuccinate synthase ArgG or Nma0303 TR:Q9JWM1 (EMBL:AL162752) (447 aa) fasta scores: E(): 0, 80.7% id in 440 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 0.993
argI
Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.984
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
 0.974
argA
Similar to Escherichia coli amino-acid acetyltransferase ArgA SW:ARGA_ECOLI (P08205) (443 aa) fasta scores: E(): 0, 87.3% id in 441 aa, and to Vibrio cholerae N-acetylglutamate synthase VC2316 TR:Q9KPQ0 (EMBL:AE004301) (456 aa) fasta scores: E(): 0, 65.8% id in 445 aa; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.929
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
 
 
 0.929
argM
Succinylornithine aminotransferase; Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
  
 
 0.795
argH
Similar to Escherichia coli argininosuccinate lyase ArgH SW:ARLY_ECOLI (P11447) (457 aa) fasta scores: E(): 0,89.0% id in 456 aa, and to Vibrio cholerae argininosuccinate lyase VC2641 TR:Q9KNT9 (EMBL:AE004330) (458 aa) fasta scores: E(): 0, 74.3% id in 456 aa.
  
  
 0.795
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
 0.742
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.740
ilvD
Similar to Escherichia coli dihydroxy-acid dehydratase IlvD SW:ILVD_ECOLI (P05791) (605 aa) fasta scores: E(): 0, 87.5% id in 616 aa, and to Salmonella typhimurium LT2 probable dihydroxy-acid dehydratase IlvD TR:Q9L6S9 (EMBL:AF233324) (616 aa) fasta scores: E(): 0,86.5% id in 616 aa; Belongs to the IlvD/Edd family.
  
 
 0.650
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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