node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A0S2LI56 | A0A0S2M5M4 | A0A0S2LI56 | A0A0S2M5M4 | PINc domain-containing protein. | Smg4_UPF3 domain-containing protein. | 0.982 |
A0A0S2LI56 | PAB1 | A0A0S2LI56 | P0CP46 | PINc domain-containing protein. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.737 |
A0A0S2LI56 | Q5K8R4_CRYNJ | A0A0S2LI56 | Q5K8R4 | PINc domain-containing protein. | DNA helicase, putative. | 0.819 |
A0A0S2LI56 | Q5K8W2_CRYNJ | A0A0S2LI56 | Q5K8W2 | PINc domain-containing protein. | Nuclear cap-binding protein subunit 2. | 0.782 |
A0A0S2LI56 | Q5KFJ7_CRYNJ | A0A0S2LI56 | Q5KFJ7 | PINc domain-containing protein. | Uncharacterized protein. | 0.730 |
A0A0S2LI56 | Q5KGH2_CRYNJ | A0A0S2LI56 | Q5KGH2 | PINc domain-containing protein. | 5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. | 0.634 |
A0A0S2LI56 | Q5KGV8_CRYNJ | A0A0S2LI56 | Q5KGV8 | PINc domain-containing protein. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.913 |
A0A0S2LI56 | Q5KJW8_CRYNJ | A0A0S2LI56 | Q5KJW8 | PINc domain-containing protein. | RNA binding protein, putative. | 0.726 |
A0A0S2LI56 | Q5KKH8_CRYNJ | A0A0S2LI56 | Q5KKH8 | PINc domain-containing protein. | ATP dependent helicase, putative. | 0.819 |
A0A0S2LI56 | Q5KMU1_CRYNJ | A0A0S2LI56 | Q5KMU1 | PINc domain-containing protein. | Uncharacterized protein. | 0.812 |
A0A0S2M5M4 | A0A0S2LI56 | A0A0S2M5M4 | A0A0S2LI56 | Smg4_UPF3 domain-containing protein. | PINc domain-containing protein. | 0.982 |
A0A0S2M5M4 | PAB1 | A0A0S2M5M4 | P0CP46 | Smg4_UPF3 domain-containing protein. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.646 |
A0A0S2M5M4 | Q5K8R4_CRYNJ | A0A0S2M5M4 | Q5K8R4 | Smg4_UPF3 domain-containing protein. | DNA helicase, putative. | 0.933 |
A0A0S2M5M4 | Q5K8W2_CRYNJ | A0A0S2M5M4 | Q5K8W2 | Smg4_UPF3 domain-containing protein. | Nuclear cap-binding protein subunit 2. | 0.824 |
A0A0S2M5M4 | Q5KFJ7_CRYNJ | A0A0S2M5M4 | Q5KFJ7 | Smg4_UPF3 domain-containing protein. | Uncharacterized protein. | 0.999 |
A0A0S2M5M4 | Q5KGH2_CRYNJ | A0A0S2M5M4 | Q5KGH2 | Smg4_UPF3 domain-containing protein. | 5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. | 0.585 |
A0A0S2M5M4 | Q5KJW8_CRYNJ | A0A0S2M5M4 | Q5KJW8 | Smg4_UPF3 domain-containing protein. | RNA binding protein, putative. | 0.969 |
A0A0S2M5M4 | Q5KKH8_CRYNJ | A0A0S2M5M4 | Q5KKH8 | Smg4_UPF3 domain-containing protein. | ATP dependent helicase, putative. | 0.994 |
A0A0S2M5M4 | Q5KMU1_CRYNJ | A0A0S2M5M4 | Q5KMU1 | Smg4_UPF3 domain-containing protein. | Uncharacterized protein. | 0.849 |
PAB1 | A0A0S2LI56 | P0CP46 | A0A0S2LI56 | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | PINc domain-containing protein. | 0.737 |