STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG1rRNA-processing protein EFG1; Involved in rRNA processing; Belongs to the EFG1 family. (286 aa)    
Predicted Functional Partners:
NOP16
Nucleolar protein 16; Involved in the biogenesis of the 60S ribosomal subunit.
   
    0.805
RRP36
rRNA biogenesis protein RRP36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
   
    0.775
Q5KKL9_CRYNJ
Uncharacterized protein.
   
 
  0.724
Q5KI91_CRYNJ
Uncharacterized protein.
   
  0.713
Q5KM38_CRYNJ
Uncharacterized protein.
   
 
  0.703
Q5KDU5_CRYNJ
Cytoplasm protein, putative.
   
 
  0.696
Q5KGV7_CRYNJ
Ribosome biogenesis and assembly-related protein, putative.
   
 
  0.690
Q5K6Y3_CRYNJ
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
   
 
  0.682
Q5KP38_CRYNJ
20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.
   
 
  0.682
Q5KKT0_CRYNJ
RIO domain-containing protein.
   
 
  0.662
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.