STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (269 aa)    
Predicted Functional Partners:
Q5KDR3_CRYNJ
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.978
Q5KHX0_CRYNJ
Adenine phosphoribosyltransferase, putative.
  
 
 0.973
Q5K6V6_CRYNJ
Adenosine kinase, putative.
  
 0.970
Q5KGK1_CRYNJ
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.969
Q5KAX0_CRYNJ
Nucleoside-diphosphate kinase, putative; Belongs to the NDK family.
  
 0.951
Q5K9A9_CRYNJ
Ribonucleoside-diphosphate reductase, putative.
   
 
 0.950
Q5KGR6_CRYNJ
Nucleoside diphosphate kinase.
  
 0.947
Q5K9L8_CRYNJ
Ribonucleotide reductase small subunit, putative.
     
 0.945
Q5KKB8_CRYNJ
AMP deaminase, putative.
   
 
 0.932
Q5KCV9_CRYNJ
Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
   
 
 0.927
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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