node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A0S2LIN1 | NTH1 | A0A0S2LIN1 | Q5KDK4 | DNA_binding_1 domain-containing protein. | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | 0.588 |
A0A0S2LIN1 | Q5K8T8_CRYNJ | A0A0S2LIN1 | Q5K8T8 | DNA_binding_1 domain-containing protein. | DNA-3-methyladenine glycosidase, putative. | 0.485 |
A0A0S2LIN1 | Q5KLH0_CRYNJ | A0A0S2LIN1 | Q5KLH0 | DNA_binding_1 domain-containing protein. | 3'-5' exonuclease domain-containing protein. | 0.442 |
A0A0S2LIZ8 | NTH1 | A0A0S2LIZ8 | Q5KDK4 | Uncharacterized protein. | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | 0.641 |
A0A0S2LIZ8 | Q5K7Q1_CRYNJ | A0A0S2LIZ8 | Q5K7Q1 | Uncharacterized protein. | Uncharacterized protein. | 0.549 |
A0A0S2LIZ8 | Q5K8T8_CRYNJ | A0A0S2LIZ8 | Q5K8T8 | Uncharacterized protein. | DNA-3-methyladenine glycosidase, putative. | 0.620 |
A0A0S2LIZ8 | Q5KB21_CRYNJ | A0A0S2LIZ8 | Q5KB21 | Uncharacterized protein. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. | 0.740 |
A0A0S2LIZ8 | Q5KCJ9_CRYNJ | A0A0S2LIZ8 | Q5KCJ9 | Uncharacterized protein. | DNA-(Apurinic or apyrimidinic site) lyase, putative. | 0.523 |
A0A0S2LIZ8 | Q5KLH0_CRYNJ | A0A0S2LIZ8 | Q5KLH0 | Uncharacterized protein. | 3'-5' exonuclease domain-containing protein. | 0.668 |
MTAP_CRYNJ | Q5K8T8_CRYNJ | Q5KPU2 | Q5K8T8 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | DNA-3-methyladenine glycosidase, putative. | 0.636 |
MTAP_CRYNJ | Q5KEW3_CRYNJ | Q5KPU2 | Q5KEW3 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uncharacterized protein. | 0.743 |
MTAP_CRYNJ | Q5KI37_CRYNJ | Q5KPU2 | Q5KI37 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Vacuolar protein, putative. | 0.743 |
NTH1 | A0A0S2LIN1 | Q5KDK4 | A0A0S2LIN1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | DNA_binding_1 domain-containing protein. | 0.588 |
NTH1 | A0A0S2LIZ8 | Q5KDK4 | A0A0S2LIZ8 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | Uncharacterized protein. | 0.641 |
NTH1 | Q5K7Q1_CRYNJ | Q5KDK4 | Q5K7Q1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | Uncharacterized protein. | 0.548 |
NTH1 | Q5K8T8_CRYNJ | Q5KDK4 | Q5K8T8 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | DNA-3-methyladenine glycosidase, putative. | 0.446 |
NTH1 | Q5KB21_CRYNJ | Q5KDK4 | Q5KB21 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. | 0.910 |
NTH1 | Q5KCJ9_CRYNJ | Q5KDK4 | Q5KCJ9 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | DNA-(Apurinic or apyrimidinic site) lyase, putative. | 0.803 |
NTH1 | Q5KLH0_CRYNJ | Q5KDK4 | Q5KLH0 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. | 3'-5' exonuclease domain-containing protein. | 0.591 |
Q5K7Q1_CRYNJ | A0A0S2LIZ8 | Q5K7Q1 | A0A0S2LIZ8 | Uncharacterized protein. | Uncharacterized protein. | 0.549 |