STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KAY9_CRYNJProtein-serine/threonine kinase. (446 aa)    
Predicted Functional Partners:
Q5KIM3_CRYNJ
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.850
Q5KES4_CRYNJ
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.771
Q5K8I1_CRYNJ
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.743
Q5KHN7_CRYNJ
Dihydrolipoyl dehydrogenase.
    
 0.718
Q5KEE0_CRYNJ
Pyruvate dehydrogenase protein x component, mitochondrial, putative.
   
 0.691
Q5KDL3_CRYNJ
Endopeptidase, putative; Belongs to the AAA ATPase family.
 
    
 0.481
Q5KP83_CRYNJ
Pyruvate dehydrogenase (Acetyl-transferring), putative.
    
 0.461
Q5KNC7_CRYNJ
Electron carrier, putative; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 
 0.439
Q5K7R5_CRYNJ
Transferase, putative.
   
 
 0.436
Q5KPD3_CRYNJ
Ubiquitin-dependent protein catabolism-related protein, putative.
  
  
 0.416
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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