STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KD63_CRYNJCheckpoint protein; Belongs to the HUS1 family. (304 aa)    
Predicted Functional Partners:
Q5KH95_CRYNJ
Expressed protein.
    
 0.999
Q5KLG2_CRYNJ
Expressed protein.
   
 0.999
Q5KLS8_CRYNJ
RAD17 isoform 4, putative.
   
 0.991
Q5KCE8_CRYNJ
Activator 1 41 kDa subunit, putative.
   
 0.983
Q5KLH0_CRYNJ
3'-5' exonuclease domain-containing protein.
   
 0.983
Q5KDX5_CRYNJ
Activator 1 40 kDa subunit, putative.
    
 0.979
Q5KLQ5_CRYNJ
DNA clamp loader, putative.
    
 0.973
Q5K796_CRYNJ
DNA replication factor, putative.
   
 0.964
Q5KGM7_CRYNJ
UVSB PI-3 kinase, putative; Belongs to the PI3/PI4-kinase family.
   
 0.871
Q5KIJ9_CRYNJ
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.859
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.