STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KEC5_CRYNJPutative phospholipase. (439 aa)    
Predicted Functional Partners:
PAC1
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck; Belongs to the WD repeat LIS1/nudF family.
     
 0.918
Q5KPB8_CRYNJ
Endoplasmic reticulum protein, putative; Belongs to the membrane-bound acyltransferase family.
     
  0.900
Q5KBM6_CRYNJ
Zn(2)-C6 fungal-type domain-containing protein.
      
 0.614
Q5KF71_CRYNJ
Glucosamine 6-phosphate N-acetyltransferase, putative.
      
 0.614
Q5KIS2_CRYNJ
Expressed protein.
      
 0.614
PLPL_CRYNJ
Patatin-like phospholipase domain-containing protein CNE02340; Probable lipid hydrolase; Belongs to the PLPL family.
    
 
 0.456
Q5K906_CRYNJ
AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
      
 0.454
Q5KKW5_CRYNJ
Uncharacterized protein.
      
 0.447
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.