STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KEY4_CRYNJRING-CH-type domain-containing protein. (1541 aa)    
Predicted Functional Partners:
Q5KA71_CRYNJ
MMS2, putative; Belongs to the AAA ATPase family.
    
 
 0.979
FPR4
FK506-binding protein 4; PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. Proline isomerization influences H3 methylation thereby regulating gene expression.
   
 
 0.850
Q5KGN1_CRYNJ
Ubiquitin conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.826
Q5KCK0_CRYNJ
RING-type domain-containing protein.
    
 
 0.810
Q5KFD4_CRYNJ
Ubiquitin-conjugating enzyme E2-28.4KD, putative.
    
 
 0.802
Q5KE28_CRYNJ
Uncharacterized protein.
    
 
 0.744
Q5KCQ0_CRYNJ
Expressed protein.
    
 
 0.738
Q5KKD7_CRYNJ
NOT2_3_5 domain-containing protein.
    
 
 0.738
Q5KFX3_CRYNJ
UAS domain-containing protein.
    
 
 0.717
Q5KGG9_CRYNJ
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.694
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.