STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KF34_CRYNJG-patch domain-containing protein. (1019 aa)    
Predicted Functional Partners:
Q5KEX1_CRYNJ
Pre-mRNA splicing factor, putative.
   
 0.997
CLF1
Pre-mRNA-splicing factor CLF1; Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
   
  0.995
Q5K8Y6_CRYNJ
Bud site selection-related protein, putative.
    
 
 0.988
Q5KIQ1_CRYNJ
116 kDa u5 small nuclear ribonucleoprotein component, putative.
   
 
 0.966
Q5KDZ3_CRYNJ
Pre-mRNA splicing factor, putative.
   
 0.961
Q5KCA1_CRYNJ
Uncharacterized protein.
    
  0.956
Q5KPW2_CRYNJ
Splicing factor Prp8, putative.
   
 
 0.956
SYF1
Pre-mRNA-splicing factor SYF1; Involved in pre-mRNA splicing and cell cycle progression.
   
 0.952
Q5KFU9_CRYNJ
Uncharacterized protein.
   
 0.951
CWC2
Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]
    
  0.928
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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