STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KFM2_CRYNJUBIQUITIN_CONJUGAT_2 domain-containing protein. (956 aa)    
Predicted Functional Partners:
Q5KIA2_CRYNJ
HECT domain-containing protein.
   
 0.896
Q5KPX3_CRYNJ
Ubiquitin activating enzyme, putative.
  
 0.786
Q5KFR2_CRYNJ
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.767
Q5KEU0_CRYNJ
Ubiquitin conjugating enzyme, putative.
     
 0.752
Q5KAU2_CRYNJ
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.707
Q5KFD4_CRYNJ
Ubiquitin-conjugating enzyme E2-28.4KD, putative.
    
 0.705
Q5KKS5_CRYNJ
NEDD8 activating enzyme, putative.
   
 0.703
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 0.697
Q5KPQ5_CRYNJ
RanBD1 domain-containing protein.
   
 0.672
Q5KGK7_CRYNJ
Ubiquitin conjugating enzyme, putative.
     
 0.666
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.