STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KKG3_CRYNJExpressed protein. (109 aa)    
Predicted Functional Partners:
DFR1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family.
  
 
 0.628
Q5KK40_CRYNJ
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.428
Q5KK20_CRYNJ
Pyr_redox_2 domain-containing protein.
  
 0.422
Q5K955_CRYNJ
Sulfide:quinone oxidoreductase, mitochondrial, putative.
  
 0.420
Q5KC39_CRYNJ
Oxidoreductase, putative.
   
 0.419
Q5KKE2_CRYNJ
Rieske domain-containing protein.
   
 0.419
Q5KLY3_CRYNJ
Oxidoreductase, putative.
   
 0.419
Q5KNX2_CRYNJ
Pyr_redox_2 domain-containing protein.
   
 0.419
Q5KIU1_CRYNJ
DAO domain-containing protein.
  
 0.416
A0A0S2LIJ3
Uncharacterized protein.
  
 0.409
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.