STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KKH7_CRYNJOxaloacetate carrier, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)    
Predicted Functional Partners:
MKAR_CRYNJ
Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.616
Q5KJ09_CRYNJ
Golgi to vacuole transport-related protein, putative.
   
    0.590
Q5KPM3_CRYNJ
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
   
  
 0.580
Q5KBW0_CRYNJ
Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.
   
    0.573
Q5KNT3_CRYNJ
Casein kinase I, putative; Belongs to the protein kinase superfamily.
   
    0.515
Q5K7H6_CRYNJ
Protein disulfide-isomerase.
   
    0.499
Q5KIZ1_CRYNJ
Dolichyl-phosphate-mannose-protein mannosyltransferase, putative.
   
  
 0.412
Q5KEU2_CRYNJ
Oxysterol binding protein, putative; Belongs to the OSBP family.
   
    0.405
Q5KKT3_CRYNJ
Uncharacterized protein.
   
 
 0.405
Q5KL42_CRYNJ
T-complex protein 1, alpha subunit (Tcp-1-alpha), putative.
 
 
    0.402
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.