STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KKQ0_CRYNJHydroxymethylbilane synthase, putative. (481 aa)    
Predicted Functional Partners:
Q5K9B7_CRYNJ
Uroporphyrinogen-III synthase, putative.
  
 0.998
Q5KP99_CRYNJ
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.998
Q5K870_CRYNJ
Uroporphyrin-III C-methyltransferase, putative.
 
 0.962
Q5KMY7_CRYNJ
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 0.934
Q5KFS3_CRYNJ
Expressed protein.
  
 
 0.870
Q5KFH8_CRYNJ
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.752
Q5KJH4_CRYNJ
FSH1 domain-containing protein.
  
 
 0.729
Q5KH76_CRYNJ
Coproporphyrinogen oxidase, putative.
  
  
 0.706
DFR1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family.
  
 
 0.702
Q5KDI9_CRYNJ
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
  
 0.690
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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