STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KLJ0_CRYNJCHL1 helicase, putative. (885 aa)    
Predicted Functional Partners:
Q5KLH0_CRYNJ
3'-5' exonuclease domain-containing protein.
  
 0.979
SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72; Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1); Belongs to the SSU72 phosphatase family.
    
   0.954
Q5KFF7_CRYNJ
Cleavage/polyadenylation specificity factor, putative.
    
   0.954
Q5KNM9_CRYNJ
General RNA polymerase II transcription factor, putative.
   
 0.951
Q5KKG0_CRYNJ
Expressed protein.
   
 0.947
Q5KBR5_CRYNJ
General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.
    
 0.946
Q5K848_CRYNJ
Uncharacterized protein.
    
 0.945
Q5K741_CRYNJ
RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.943
Q5KFQ4_CRYNJ
Transcription/repair factor TFIIH subunit Tfb3, putative.
    
 0.943
Q5K6Z2_CRYNJ
Cyclin-dependent protein kinase, putative; Belongs to the protein kinase superfamily.
    
 0.940
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.