STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KLM7_CRYNJGlutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (152 aa)    
Predicted Functional Partners:
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
   
 
 0.912
Q5KAA3_CRYNJ
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.827
Q5KDZ6_CRYNJ
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.819
Q5KKU8_CRYNJ
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
      0.800
Q5KLT2_CRYNJ
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.776
Q5KGD0_CRYNJ
Iron ion transport-related protein, putative.
  
 0.770
Q5KP00_CRYNJ
Expressed protein.
  
 0.761
Q5KJS4_CRYNJ
Cytoplasm protein, putative.
   
 
 0.673
Q5KMU3_CRYNJ
Threonine-tRNA ligase, putative.
   
 
 0.673
Q5KE33_CRYNJ
Iron ion homeostasis-related protein, putative.
   
 
 0.646
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.