STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KMW2_CRYNJFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)    
Predicted Functional Partners:
Q5KG36_CRYNJ
Triosephosphate isomerase.
  
 
 0.996
Q5KAN4_CRYNJ
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
  
 
 0.984
Q5KE01_CRYNJ
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 0.982
GPD
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.978
Q5KC42_CRYNJ
Glyceraldehyde-3-phosphate dehydrogenase.
  
 0.977
Q5KLU5_CRYNJ
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.976
Q5KQ48_CRYNJ
Fructose-bisphosphatase, putative; Belongs to the FBPase class 1 family.
  
 
 0.976
Q5KLA7_CRYNJ
Phosphopyruvate hydratase, putative.
  
 0.973
Q5KG11_CRYNJ
Enolase 1, putative.
  
 0.972
Q5KJ21_CRYNJ
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.968
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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