STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5KNM8_CRYNJCytosine deaminase, putative. (165 aa)    
Predicted Functional Partners:
Q5KGW5_CRYNJ
Uracil phosphoribosyltransferase 1, putative.
   
 
 0.944
Q5KGX1_CRYNJ
Uracil phosphoribosyltransferase, putative.
   
 
 0.926
Q5KCW2_CRYNJ
PfkB domain-containing protein.
     
  0.900
Q5KK48_CRYNJ
SET domain-containing protein.
   
 0.654
Q5KJY3_CRYNJ
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
 0.647
Q5KE08_CRYNJ
Uridine kinase; Belongs to the uridine kinase family.
   
 
 0.589
DFR1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family.
  
 
 0.550
Q5KMP7_CRYNJ
dCMP deaminase, putative.
      
 0.530
Q5KB67_CRYNJ
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
   
 
 0.475
TMP1
Thymidylate synthase.
  
 
 0.428
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.