DBP8 protein (Cryptococcus neoformans) - STRING interaction network

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DBP8

ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily. (619 aa)

Predicted Functional Partners:

Q5K764_CRYNJ

0.998

Q5KNB9_CRYNJ

0.992

ESF2

0.986

Q5KIJ7_CRYNJ

0.985

Q5KEA3_CRYNJ

0.982

Q5KMT6_CRYNJ

0.981

ROK1

0.979

Q5KAE4_CRYNJ

0.978

Q5KH56_CRYNJ

0.978

Q5KEP9_CRYNJ

0.972

Your Current Organism:

Cryptococcus neoformans

NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DBP8	ESF2	P0CR02	P0CL96	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	0.986
DBP8	Q5K764_CRYNJ	P0CR02	Q5K764	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	Sas10 domain-containing protein.	0.998
DBP8	Q5KAE4_CRYNJ	P0CR02	Q5KAE4	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	Nucleolar essential protein 1, putative.	0.978
DBP8	Q5KEA3_CRYNJ	P0CR02	Q5KEA3	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	0.982
DBP8	Q5KEP9_CRYNJ	P0CR02	Q5KEP9	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	CBF domain-containing protein.	0.972
DBP8	Q5KH56_CRYNJ	P0CR02	Q5KH56	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	rRNA processing-related protein, putative.	0.978
DBP8	Q5KIJ7_CRYNJ	P0CR02	Q5KIJ7	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	U3 small nucleolar RNA-associated protein 22.	0.985
DBP8	Q5KMT6_CRYNJ	P0CR02	Q5KMT6	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.981
DBP8	Q5KNB9_CRYNJ	P0CR02	Q5KNB9	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	ATP-dependent RNA helicase prh1, putative.	0.992
DBP8	ROK1	P0CR02	P0CR04	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	ATP-dependent RNA helicase ROK1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.	0.979
ESF2	DBP8	P0CL96	P0CR02	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	0.986
ESF2	Q5K764_CRYNJ	P0CL96	Q5K764	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	Sas10 domain-containing protein.	0.416
ESF2	Q5KAE4_CRYNJ	P0CL96	Q5KAE4	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	Nucleolar essential protein 1, putative.	0.436
ESF2	Q5KEA3_CRYNJ	P0CL96	Q5KEA3	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	0.985
ESF2	Q5KH56_CRYNJ	P0CL96	Q5KH56	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	rRNA processing-related protein, putative.	0.546
ESF2	Q5KMT6_CRYNJ	P0CL96	Q5KMT6	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	WD_REPEATS_REGION domain-containing protein.	0.411
ESF2	Q5KNB9_CRYNJ	P0CL96	Q5KNB9	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	ATP-dependent RNA helicase prh1, putative.	0.442
ESF2	ROK1	P0CL96	P0CR04	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	ATP-dependent RNA helicase ROK1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.	0.728
Q5K764_CRYNJ	DBP8	Q5K764	P0CR02	Sas10 domain-containing protein.	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	0.998
Q5K764_CRYNJ	ESF2	Q5K764	P0CL96	Sas10 domain-containing protein.	Pre-rRNA-processing protein ESF2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family.	0.416

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