STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COX19Cytochrome c oxidase assembly protein COX19; Required for the assembly of mitochondrial cytochrome c oxidase; Belongs to the COX19 family. (115 aa)    
Predicted Functional Partners:
Q5KCT7_CRYNJ
Uncharacterized protein.
   
 
 0.646
Q5KLL5_CRYNJ
Aerobic respiration-related protein, putative.
    
 
 0.607
MIA40
Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...]
   
 0.564
Q5KJR5_CRYNJ
COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family.
   
  
 0.564
COX23
Cytochrome c oxidase-assembly factor COX23, mitochondrial; Required for the assembly of cytochrome c oxidase. Belongs to the COX23 family.
   
  
 0.510
Q5KJG6_CRYNJ
Lactamase_B domain-containing protein.
   
 0.418
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.