STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CWC27Peptidyl-prolyl isomerase CWC27; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity). Belongs to the cyclophilin-type PPIase family. CWC27 subfamily. (491 aa)    
Predicted Functional Partners:
CEF1
Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.
    
 
 0.993
Q5KET5_CRYNJ
Pre-mRNA splicing factor, putative.
   
 0.993
Q5KKN8_CRYNJ
Nuclear matrix protein NMP200, putative.
    
 0.991
CWC22
Pre-mRNA-splicing factor CWC22; Involved in pre-mRNA splicing.
   
 0.987
CWC24
Pre-mRNA-splicing factor CWC24; Involved in pre-mRNA splicing.
    
 0.982
Q5KKN7_CRYNJ
Pre-mRNA splicing factor, putative.
   
 0.971
Q5K8Y6_CRYNJ
Bud site selection-related protein, putative.
    
 0.961
Q5KDZ3_CRYNJ
Pre-mRNA splicing factor, putative.
    
 0.957
CWC26
Pre-mRNA-splicing factor CWC26; Involved in pre-mRNA splicing.
    
 0.942
PRP45
Pre-mRNA-processing protein 45; Involved in pre-mRNA splicing.
   
 0.931
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.