STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FPR1FK506-binding protein 1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the FKBP-type PPIase family. FKBP1 subfamily. (108 aa)    
Predicted Functional Partners:
CNB1
Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. Plays a central role in virulence and antifungal drug action.
   
 0.996
Q5KAC2_CRYNJ
Serine/threonine-protein phosphatase.
    
 0.996
Q5KJP4_CRYNJ
Shuttle craft like transcriptional regulator, putative.
   
 
 0.872
CYP3
Peptidyl-prolyl cis-trans isomerase H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
 
 0.862
CPR2
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
 
 0.853
Q5KML4_CRYNJ
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
 0.838
Q5K8Y1_CRYNJ
Phosphatidylinositol 3-kinase, putative; Belongs to the PI3/PI4-kinase family.
    
 
 0.830
Q5KEY7_CRYNJ
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 
 0.830
Q5KJK0_CRYNJ
Uncharacterized protein; Belongs to the calmodulin family.
   
 0.830
Q5KH63_CRYNJ
Uncharacterized protein.
   
 0.823
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.