STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPL4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (693 aa)    
Predicted Functional Partners:
Q5K7Q1_CRYNJ
Uncharacterized protein.
   
 0.999
Q5K888_CRYNJ
Ubiquitin fusion-degradation 1-like protein, putative.
   
 0.999
Q5KA71_CRYNJ
MMS2, putative; Belongs to the AAA ATPase family.
   
 0.999
Q5K766_CRYNJ
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 0.986
Q5K8K4_CRYNJ
Phospholipase A-2-activating protein, putative.
   
 
 0.986
A0A0S2LIV9
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 0.983
Q5K710_CRYNJ
OTU domain-containing protein.
   
 
 0.982
Q5K8W1_CRYNJ
U-box domain-containing protein.
    
 
 0.977
Q5KFX3_CRYNJ
UAS domain-containing protein.
    
 
 0.964
Q5KE28_CRYNJ
Uncharacterized protein.
   
 0.951
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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