STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDC80Probable kinetochore protein NDC80; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (703 aa)    
Predicted Functional Partners:
NUF2
Probable kinetochore protein NUF2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
  
 0.999
SPC25
Probable kinetochore protein SPC25; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
   
 0.999
Q5KP59_CRYNJ
Expressed protein.
   
 0.993
Q5KE09_CRYNJ
Mitotic spindle assembly-related protein, putative.
    
 
 0.983
Q5KDI6_CRYNJ
Protein kinase, putative.
   
 0.972
Q5KKX5_CRYNJ
Mitotic spindle checkpoint-related protein, putative.
   
 0.942
Q5KDF5_CRYNJ
Structural maintenance of chromosomes protein.
   
 
 0.902
Q5KMS4_CRYNJ
Cysteine-type endopeptidase, putative.
   
 
 0.891
Q5KE89_CRYNJ
Microtubule motor, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.890
Q5KI66_CRYNJ
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.885
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.