STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A316YM42SH3 domain-containing protein. (273 aa)    
Predicted Functional Partners:
A0A316YQQ4
Actin/actin-like protein; Belongs to the actin family.
    
 0.823
A0A316YWB7
Uncharacterized protein.
   
 0.817
A0A316YLB1
Uncharacterized protein.
    
 0.809
A0A316YIM1
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.796
A0A316YT66
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
 0.796
A0A316YI85
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.795
A0A316YP74
Putative ARP3-actin related protein; Belongs to the actin family.
   
 0.790
A0A316YZC5
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.788
A0A316YVJ2
Uncharacterized protein.
    
 0.780
A0A316YMI3
Putative dynactin Arp1 p25 subunit RO12.
    
 0.777
Your Current Organism:
Acaromyces ingoldii
NCBI taxonomy Id: 215250
Other names: A. ingoldii, AS001, CBS 110050
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